Rapid weight gain during infancy and pubic hair development onset in boys from a contemporary British cohort. Público
Noory, Laila Sara (2010)
Abstract
Abstract
Rapid weight gain during infancy and pubic hair development onset
in boys from a contemporary British cohort.
By Laila Sara Noory
Specific Aims
The aim of the present study is to describe the relationship between weight gain during infancy and the entry into stage 2 or higher of pubic hair development in boys. The boys were enrolled prenatally from 1991-1992 in the Avon Longitudinal Study of Parents and Children (ALSPAC) who responded to the Growing and Changing questionnaire. Data was gathered on their self-assessed pubertal status between 8 and 14 years of age.
Methods
Repeated self-assessments of pubertal development were obtained from 3,938 boys between the ages of 8-14. Data on prenatal characteristics and weight at birth, 2, 9 and 20 months were obtained from questionnaires, birth records and clinic visits for 1,816 boys. Infant's weights were converted to weight-for-age SD scores and change values were obtained for age intervals from birth to 2 months, 2 to 9 months, 9 to 20 months and birth to 20 months. Parametric survival models were used to estimate associations with age of entry into Tanner stage 2 of pubic hair development.
Results
Maternal age at delivery, smoking in the 3rd trimester, primiparity and breastfeeding were individually associated with puberty onset. The adjusted model showed a 1-unit increase in the weight-SD-score change for the birth to 20 months age interval was associated with an earlier age of entry into stage 2 of pubic hair development (-0.11 years).
Conclusion
A few maternal prenatal and postnatal characteristics, along with weight gain during infancy, appear to be involved in the onset of puberty. These early fetal and infancy factors may play a role in the timing of puberty in boys.
Table of Contents
Table of Contents
1. Background...1
2. Methods...9
3. Results...12
4. Discussion...15
5. Strengths and Weaknesses...19
6. Future Directions...20
7. References...21
8. Tables...27
9. Appendix...35
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