The Association Between Birth Control Use and Metabolic Profiles of Women Residing in the United States (NHANES 2015 - 2016) Público
Rivera, Guadalupe (Spring 2024)
Published
Abstract
Introduction: With the increased use of hormonal contraceptives among women in the United
States, alongside the linkage between reproductive hormones and metabolic disease, it is
important to understand if the use of birth control impacts metabolic profiles in women. While
there is previous research on the effects of birth control history in menopausal women, there is
less research in women who are of reproductive age. The objective of this research is to conduct
cross-sectional descriptive analysis of five metabolic outcomes according to women’s history of
birth control usage.
Methods: Data were from the nationally representative National Health and Nutrition
Examination Survey (NHANES) 2015-2016. The study population comprised non-pregnant
women aged 20-44 years in the United States. We compared metabolic measures between those
who have ever used birth control and those who have not. Differences by birth control history in
total cholesterol, systolic blood pressure, Body Mass Index (BMI), waist circumference, and
glycohemoglobin levels were modeled using linear and quantile regression.
Results: A total 694 women with mean age 32.5 were included in the analysis; 66.57% reported
a minority race and ethnicity background. 67.44% reported history of birth control use. In
adjusted regression models, women who had used birth control had, on average, a 3.17 mmHg
(95%CI) higher systolic blood pressure compared to those who had never used birth control.
There were no other statistically significant differences in metabolic measures between women
who had ever or never used birth control.
Discussion: In a diverse group of US women, we found that women with a history of birth
control had higher systolic blood pressure. Findings motivate further research on the role of birth
control in hypertension development and the appropriateness of birth control among women at
high risk for hypertension.
Table of Contents
INTRODUCTION 1
LITERATURE REVIEW 2
BIRTH CONTROL USE IN THE UNITED STATES 2
PATHWAYS LINKING CONTRACEPTIVE USE TO METABOLIC HEALTH 4
Weight and Body Mass Index 4
Birth Control Use and Glycohemoglobin 5
Hypertension 5
Hyperlipidemia 6
BIRTH CONTROL USE AND METABOLIC OUTCOMES 7
SCIENTIFIC PREMISE 7
METHODS 8
STUDY POPULATION 8
STUDY MEASURES 9
RESULTS 12
CONCLUSION 18
REFERENCES 20
TABLES AND FIGURES 23
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