Measuring Vaccine Confidence in a Pilot Introduction of Human Papillomavirus (HPV) in Cambodia Público
Jaggi, Chandni (Spring 2018)
Abstract
Introduction: Vaccine confidence is becoming increasingly important to study, as vaccine refusal has been increasing in high-income countries. While vaccine confidence has been assessed in high-income countries, there have been few studies on measuring vaccine confidence in low and middle-income countries. As vaccination rates continue to increase in low and middle-income countries, monitoring vaccine confidence is import for ensuring high vaccine uptake. An HPV vaccine demonstration program in Cambodia done by the CDC allowed for us to measure vaccine confidence in this context.
Methods: Respondent demographics and vaccine confidence data were collected during an HPV vaccine demonstration program coverage survey in Cambodia. Four constructs were used to measure vaccine confidence: “I believe vaccines are important,” “I believe vaccines are safe,” “I believe vaccines are effective,” and “I believe vaccines are compatible with my religious beliefs.” Respondents were asked to respond on whether they agreed or disagreed with each statement or didn’t know, and those responses were coded as 1-no, 2-I don’t know, and 3-yes. A Vaccine Confidence Summary Score (VCSS) was created as the sum of each respondents’ answers to the four questions. Associations between vaccine uptake and vaccine confidence were measured.
Results: There were a total of 316 respondents in the survey, of which 312 respondents answered all four vaccine confidence questions and were included in this analysis. Ninety percent of respondents agreed with all four of the vaccine confidence questions. There were no statistically significant associations found between vaccine uptake and vaccine confidence, both overall and for the individual statements.
Discussion: Overall, vaccine confidence was found to be very high in this sample in two provinces in Cambodia. There was an almost unanimous agreement among respondents that vaccines are important. There was some hesitancy documented among the other three measures, however people still overwhelmingly confident. Issues with vaccine confidence, specifically vaccine safety, have been seen in high-income countries regarding the HPV vaccine and have caused low rates of vaccine uptake. Therefore, future monitoring of vaccine confidence should continue to ensure confidence stays high and subsequently uptake remains high. Factors affecting vaccine confidence in low and middle-income countries should also be analyzed in future studies.
Table of Contents
1. Introduction ………………………………………………………………………1
2. Methods…………………………………………………………………………...3
2.1 Data Collection……………………………………………………………......3
2.2 Measures........................................................................................................... 4
2.3 Statistical Analysis…………………………………………………………….4
2.4 IRB…………………………………………………………………………….5
3. Results……………………………………………………………………………..6
4. Discussion………………………………………………………………………..13
5. References………………………………………………………………………..18
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