Age at Death Due to Sudden Infant Death Syndrome for Term and Pre-Term Infants Öffentlichkeit
Ludvigsen, Rebecca Ann (2012)
Published
Abstract
Introduction: Premature infants are at increased risk for
Sudden Infant Death Syndrome (SIDS),
the third leading cause of US infant mortality.The relationship
between gestational age at birth
and age at death among SIDS cases may have important implications
for understanding
physiological changes occurring during the critical developmental
period after birth. We
compared age at death distributions between SIDS infants born
preterm and term, and also
stratified by race and Hispanic origin and sex.
Methods: Data were obtained from the US Birth Cohort Linked
Birth/Infant Death Data Sets for
2003-2005. Analysis was restricted to singleton infants born to US
resident mothers between 28
and 41 weeks gestation, who died of SIDS in the postneonatal period
(n=5,017). SIDS cases
were identified from the death certificate underlying International
Classification of Diseases-10th
revision (ICD-10) cause-of-death code, R95. Infants were
categorized into four gestational age
categories: very preterm (28-33 weeks), late preterm (34-36 weeks),
early term (37-38 weeks),
and term gestations (39-41 weeks). We compared age at death
distributions and used Analysis of
Variance (ANOVA) to evaluate differences in mean chronological age
at death between
gestational age categories.
Results: Chronological age at death
distributions for each gestational age group peaked at
approximately 9 weeks . Mean chronological age at death of
SIDS was 15.2 weeks among very
preterm infants, 14.6 weeks among late preterm infants, 13.9 weeks
among early term infants and
14.3 weeks among term infants. Mean chronological ages at death by
gestational age group
stratified by race and Hispanic origin or infant sex were
similar.
Discussion: We report no clinically meaningful difference
between gestational age at birth and
chronological age at death for SIDS infants. Race-specific and
sex-specific findings are similar.
Use of clinically meaningful gestational age cut points provides an
insight into the relationship
between gestational age at birth and chronological age at death for
SIDS. Contrary to prior
reports, the critical window of vulnerability does not appear to be
modified by gestational age at
birth. Caregivers should be aware of the increased SIDS risk among
preterm infants, but should
practice SIDS risk reduction for all infants regardless of
gestational age at birth.
Table of Contents
Table of Contents
CHAPTER I:
LITERATURE REVIEW
......................................................................................................1
CHAPTER II
...................................................................................................................................13
ABSTRACT
.....................................................................................................................................13
INTRODUCTION
...............................................................................................................................13
METHODS
......................................................................................................................................15
RESULTS
........................................................................................................................................16
DISCUSSION
...................................................................................................................................17
REFERENCES
...................................................................................................................................23
TABLES
..........................................................................................................................................29
FIGURES
.........................................................................................................................................27
APPENDIX
......................................................................................................................................30
About this Master's Thesis
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