Diagnosed Diabetes and In-Hospital Mortality after Coronary Artery Bypass Grafting Open Access

Abstract

Background-Data are conflicting over whether patients with diagnosed diabetes mellitus (DM)
have higher in-hospital mortality than patients without diabetes after coronary artery bypass
grafting (CABG) surgery. Long-term survival is decreased in patients with diabetes after CABG. We
hypothesized that patients with diabetes have higher in-hospital mortality rates after CABG.
Methods and Results-We studied 11,001 patients (38.8% with diagnosed DM) included in the
Society of Thoracic Surgeons database who received CABG at 3 clinical centers January 1, 2002 and
December 31, 2010. Patients with DM were more likely to be non-white, obese, and female. DM
diagnosis was related to in-hospital mortality after CABG, but this relationship was dependent on age
and race. Non-white individuals under 55 years of age were 14 times more likely to die in-hospital
post-CABG if they were diagnosed with DM than if the were not diagnosed with DM (AOR= 14.10,
95% CI 1.77-112.28). White individuals under 55 years of age were no more likely to die in-hospital
dependent on positive DM diagnosis (AOR= 1.25, 95% CI 0.25-8.01). Diagnosed DM in individuals
between 55 and 69 years of age was not associated with increased likelihood of in-hospital mortality
(AOR= 0.86, 95% CI 0.49-1.51) or in individuals over 70 years of age (AOR 0.88, 95% CI 0.56-1.38).
Conclusions- Diagnosed DM was associated with higher in-hospital mortality, but this association
was limited to young (under 55 years of age) non-whites. Diagnosed DM was not associated with
increased in-hospital mortality in whites, and individuals over 55 years of age. Additional
investigation is needed to determine why in-hospital mortality is higher in those diagnosed with
diabetes after CABG, with particular focus on younger non-white individuals.

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About this Master's Thesis

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School	Rollins School of Public Health
Department	Epidemiology
Degree	MPH
Submission	Master's Thesis
Language	English
Research Field	Health Sciences, Public Health Health Sciences, Epidemiology
Keyword	age CABG Diabetes race Mortality
Committee Chair / Thesis Advisor	Goodman, Michael, Emory University
Committee Members	Kilgo, Patrick D, Emory University
Partnering Agencies	Does not apply (no collaborating organization)

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