A composite measure and analysis of adolescent HPV, MenACWY, and Tdap vaccine coverage, as recorded by the National immunization Survey - Teen, United States, 2020 Pubblico

Kennicker, Jessica (Spring 2023)

Permanent URL: https://etd.library.emory.edu/concern/etds/qr46r2362?locale=it
Published

Abstract

Background: An analysis of adolescent vaccine uptake, according to the Advisory Committee on Immunization Practices (ACIP) recommendations, is generally a siloed process, with comparisons of uptake for each of the three vaccines -human papillomavirus (HPV), meningococcal meningitis (MenACWY), and tetanus, diphtheria, and acellular pertussis (Tdap) – reported separately. Coverage estimates are not combined to differentiate completely vaccinated adolescents from the un- and undervaccinated.

Methods: This is a secondary analysis of the 2020 NIS-Teen provider data, with the primary outcome being a composite measure of all three adolescent vaccines, and analysis stratified by key socio-demographic characteristics to identify population subgroup-level differences in total adolescent vaccine uptake. All analysis was conducted using appropriate complex survey analysis methods (e.g., SAS PROC SURVEYFREQ), which were weighted, and 95% confidence intervals applied. Then stratified results were reviewed independently and compared to past trends of the same variables by each of the three vaccines.

Results:  In 2020, uptake of Tdap (90.1%) and MenACWY (89.7%) vaccines among adolescents reached the Healthy People 2020 targets of 80.0%, but HPV vaccine uptake is still far from that goal (58.6%). When considered across all adolescent vaccines, complete vaccine coverage was only 55.2%. The groups that were the least likely to be fully vaccinated were the most likely to be vaccinated only with Tdap and MenACWY vaccines. For example, Hispanic adolescents were the most likely to be up to date with all vaccines (58.1%), with the lowest completed vaccination among non-Hispanic White adolescents (53.1%); non-Hispanic White adolescents were more likely to have received only Tdap and MenACWY vaccines (33.9% versus 25.5% for Hispanic adolescents). Females were more likely than males to be completely up to date on adolescent vaccines, 57.9% versus 52.6%, respectively.

Discussion:  Coverage disparities such as these may not be fully recognized when the data is not evaluated in aggregate. Consideration of gaps that prevent adolescents from being adequately vaccinated can highlight factors contributing to increased vaccine uptake, such as provider recommendations, and apply them in areas with coverage gaps. Populations with incomplete coverage can be identified and vaccine promotion campaigns can be specifically targeted to those groups. 

Table of Contents

Table of Contents

Introduction: 1

Literature Review: 4

Manuscripts/Results: 16

           Manuscript Title Page: 17

           Abstract: 18

           Introduction: 20

           Methods: 21

           Results: 23

           Discussion: 25

           References: 31

           Tables: 39

Implications: 44

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