Social Support and Mental Stress-Induced Myocardial Ischemia Following a Myocardial Infarction Open Access

Abstract

Introduction: Coronary artery disease (CAD) is an important public health issue. One of the manifestations of CAD is myocardial ischemia, which can be induced through mental stress or physical stressors such as exercise. Lack of social support has been identified as a psychosocial risk factor of CAD. The purpose of this analysis was to evaluate the role of social support in mental stress ischemia (MSI) and determine any sex differences.

Methods: Secondary analysis of the Myocardial Infarction and Mental Stress (MIMS) study, a cross-sectional study of 98 young (<60 years old) patients with a previous MI who have all undergone mental stress testing. Perfusion imaging scores at rest, after mental stress and after exercise stress were used to quantify ischemia under both stress conditions. Social support was measured with the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Social Support Inventory (ESSI). The ESSI score was analyzed as a continuous variable and divided into tertiles.

Results: We found a small inverse relationship between mental stress ischemia and ESSI score, but relationship was not statistically significant. The results were similar in men and women.

Conclusion: No association was found between social support and MSI and no sex differences were evident.

Table of Contents

Introduction...1 Methods...4 Results...7 Discussion...10 References...13 Table 1...18 Table 2...19 Table 3...20 Table 4...21 Table 5...22 Table 6...23 Table 7...23

About this Master's Thesis

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School	Rollins School of Public Health
Department	Epidemiology
Degree	MPH
Submission	Master's Thesis
Language	English
Research Field	Health Sciences, Epidemiology
Keyword	social support mental stress ischemia coronary artery disease
Committee Chair / Thesis Advisor	Vaccarino, Viola, Emory University
Partnering Agencies	Emory University schools, faculty or affiliated programs

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