The Development and Implementation of a Chemical Banding Program to Minimize Worker Risk Associated with the Use of Chemicals in Research Animals Open Access
Hubble, Leslie (2010)
Abstract
The Development and Implementation of a Chemical Banding
Program to Minimize
Worker Risk Associated with the Use of Chemicals in Research
Animals
By Leslie M. Hubble
Chemical and pharmaceutical
industries have led the way in chemical risk
classification systems also known as chemical banding systems.
Industry primarily uses
chemical banding for quantitative exposure monitoring. Chemical
industries can approach
chemical risk management in this fashion, because they typically
work with a finite number
of chemicals which often have established occupational exposure
limits. In contrast,
scientific research at a University with an academic medical center
can involve thousands of
chemicals, many with unknown exposure limits and unknown monitoring
methods. The
frequent use of chemicals for this research can increase the
relative risk and increases the
need for qualitative chemical risk assessment and mitigation.
Exposure risk becomes more
difficult to assess, quantify, and control when these chemical are
used animal research. The
chemicals used in animal research are typically toxic,
carcinogenic, etc. and are often used to
induce or treat adverse health outcomes.
The following paper outlines a program that was designed and
implemented in
conjunction with Emory University's Environmental Health and Safety
Office (EHSO) and
Division of Animal Resources (DAR) to meet the intent of
Occupational Health and Safety
Administration (OSHA) standards and the recommendations of
Association for Assessment
and Accreditation of Laboratory Animal Care International (AAALAC).
This Chemical
Banding program establishes a qualitative risk assessment method
for controlling risk in the
animal facility associated with chemical research in animals. The
program establishes
appropriate exposure controls to match each level of presumed risk.
The program has been
implemented with such control measures as protocol approval,
personnel training, and
hazard signage to identify areas where chemicals are being
administered to animals.
Chemicals of unknown toxicity and nanomaterials present a challenge
as the risk
associated with these materials is not well characterized. Since
quantifying this risk is
resource intensive in terms of time and cost; the risk assessment
and control method
presented in this document is a good foundation for mitigating the
potential chemical risk to
workers in animal research.
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