Feasibility of a dietary intervention with a Paleolithic diet-compatible food product Open Access

Graciaa, Daniel (2014)

Permanent URL: https://etd.library.emory.edu/concern/etds/cz30pt30r?locale=en


Objective: Previous trials of the Paleolithic diet have found improvement in metabolic and cardiovascular health indicators. We sought to evaluate the feasibility of using a pre-packaged food product compatible with the Paleolithic diet as a single-meal dietary intervention.

Methods: Healthy volunteers (n=22) replaced their midday meal with 16oz of Chuice, a bottled combination of unpasteurized, unprocessed, raw fruits, vegetables, herbs, nuts and seeds, for 14 consecutive days. The before-and-after comparisons of BMI, blood pressure, heart rate, fasting capillary blood glucose and pulse wave velocity were performed using paired t-tests and Wilcoxon related sample signed-rank tests.

Results: A total of 21 participants completed the study (95% adherence to the protocol). Pulse wave velocity decreased on average by 0.56 m/s with a 95% confidence interval between 0.00796 and 1.1063, and p values of 0.047 and 0.037 for paired t-test and Wilcoxon related samples test, respectively. There were no statistically significant differences in BMI, blood pressure, heart rate, or fasting blood glucose.

Conclusion: This pilot study suggests that the protocol is feasible, participants tolerate the intervention, and, based on preliminary findings for pulse wave velocity, a full-scale, controlled study is warranted.

Table of Contents

Background 1
Methods 4
Results 6
Discussion 8
References 11
Table 1: Ingredients and nutritional data of food product "Chuice" 16
Table 2: Baseline characteristics of study participants 17
Table 3: Outcome data for all participants completing the study 18
Table 4: Mean differences and statistical comparisons of biometric outcomes 19

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