Quality of Life and Cardiovascular Disease Risk: Does the SF-36v2 Predict Unhealthy Cholesterol in a Population of Female African American Healthcare Workers? 公开

Aguilar, Gabriela Aurora (2011)

Permanent URL: https://etd.library.emory.edu/concern/etds/cv43nx35w?locale=zh
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Abstract

Abstract

Quality of Life and Cardiovascular Disease Risk: Does the SF-36v2 Predict Unhealthy
Cholesterol in a Population of Female African American Healthcare Workers?
By Gabriela A. Aguilar


Background: Cardiovascular diseases are the number one killer of women in the
United States (1). African American women share a disproportionate disease
burden with a mortality rate nearly 1.4 times greater than that of their white
counterparts (4). A number of barriers prevent African American women from
assessing and managing their CVD risk (31). Therefore, there is much interest in
identifying an easily accessible non-laboratory-based tool for assessing CVD risk
factors such as low-density lipoprotein (LDL), high-density lipoprotein (HDL),
and total cholesterol levels.
Objective: This study examines the appropriateness of the Short Form-36™
version 2 (SF-36v2) Physical Component and Mental Health Component scores
as a risk assessment tool for high risk LDL, HDL, and total cholesterol levels.
Methods: Secondary analysis of cross-sectional data obtained from a
longitudinal physical activity intervention targeting African American female
healthcare workers.
Results: Crude prevalence ratios were statistically insignificant for the six
associations of interest. Odds ratios adjusted for socioeconomic, lifestyle, and
sociodemographic factors were also statistically insignificant.
Discussion: The data in the present study do not support the use of the SF-36v2
as an assessor of high risk cholesterol levels in the study population. Repeat
studies are needed in order to validate these results and improve generalizability
to other populations.

Table of Contents

Table of Contents


Introduction ...................................................................................................................... 3
Rationale .................................................................................................................... 3
Purpose of Study ...................................................................................................... 5
Objective and Research Questions ........................................................................ 5
Assumptions ............................................................................................................. 6
Literature Review ............................................................................................................. 7
Cardiovascular Disease in Women ....................................................................... 8
Cardiovascular Disease in African American Women ................................ 10
Cardiovascular Disease Risk Factors .................................................................. 11
Low-Density Lipoprotein ................................................................................ 16
High-Density Lipoprotein ............................................................................... 16
Total Cholesterol ............................................................................................... 17
Health-Related Quality of Life ............................................................................. 18
SF-36TM Version 2 .............................................................................................. 20
Quality of Life in African American Women ................................................ 21
Summary ................................................................................................................. 22
Methods ........................................................................................................................... 24
Target Population and Sample Participants ...................................................... 24
Procedure ................................................................................................................ 25
Measures.................................................................................................................. 27
SF-36TM Version 2 .............................................................................................. 27
Demographics .................................................................................................... 28
Body Mass Index ............................................................................................... 29
Cardiovascular Risk Factors ............................................................................ 30
Data Handling & Analysis .................................................................................... 30
Results .............................................................................................................................. 33
Discussion ....................................................................................................................... 37
Strengths & Limitations ........................................................................................ 38
Future Research ...................................................................................................... 38
Conclusions ..................................................................................................................... 40
References ....................................................................................................................... 41
Appendix ......................................................................................................................... 47

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