Temporal Dynamics of Appearance of Bacterial Colonies on Solid Surfaces Pubblico

Abstract

By observing and characterizing bacterial colony appearances on both antibiotic-free nutrient solid surfaces and surfaces with sub-lethal level antibiotics, we found that the colony appearance under the former condition follows the deterministic model of growth due to the fact that majority of colonies appeared at the same time and the spread of appearances was relatively narrow. However, the results from the latter condition can best be explained by the stochastic model since the colony appearance in this case displayed a wide spread that can be understood only after taking probability elements into consideration. This growth under the influence of sub-lethal level antibiotics was then studied in comparison to the known master equation of the stochastic model: +, and the model was fit to the data by setting parameter n (population size of a colony) to  and by inputting specific values into the birth rate  and death rate .

Table of Contents

Introduction....................................................................................................................................1

Experiment.....................................................................................................................................4

Results and Discussions................................................................................................................4

Conclusion......................................................................................................................................9

Reference........................................................................................................................................9

About this Honors Thesis

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School	Emory College
Department	Physics
Degree	B.S.
Submission	Honors Thesis
Language	English
Research Field	Physics, General Biophysics, General
Parola chiave	Microbiology
Committee Chair / Thesis Advisor	Kim, Minsu, Emory University
Committee Members	Pratt, David, Emory University Brody, Jed, Emory University

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