The association of pandemic fatigue and COVID-19 booster uptake Restricted; Files Only

Abstract

Although the primary series of COVID-19 vaccines were taken by 70% of the population in the United States, booster dose receipt didn’t come close to reaching this level of adherence. Feelings of pandemic fatigue from the COVID-19 pandemic has been discussed, but the implications on protective behavior, booster uptake, have not been assessed cross-sectionally.

Using survey data from the COVIDVu study, from August 2020 to May 2022 (N=3400), including participant demographics, pandemic fatigue Likert scaled questions, and vaccine uptake, the association between pandemic fatigue and receipt of a booster dose was assessed. Pandemic fatigue questions were categorized into two groups: disinterest and protection aversion; to understand if these two attitudes of fatigue resulted in lower booster uptake.

In unadjusted analyses, both pandemic fatigue disinterest and protection aversion were associated with not receiving a booster (0.65 and 0.78).  In adjusted analyses controlling for variables including political affiliation, a one-point increase in the level of disinterest was associated with a 30% increase in the odds of receiving a booster (disinterest: aOR, 0.72; 95% CI, 0.66-0.78); pandemic fatigue protection aversion was not associated with vaccine receipt in adjusted analyses.

Pandemic fatigue likely played a part in low receipt of booster uptake, specifically related to the feelings of disinterest towards the COVID-19 pandemic. Tailoring future national booster vaccine campaigns to the interests of the public will be essential in obtaining better adherence.

Table of Contents

Introduction ............................................................................. 1 Methods .................................................................................. 1 Results .................................................................................... 5 Discussion ............................................................................... 5

About this Master's Thesis

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• Permission granted by the author to include this thesis or dissertation in this repository. All rights reserved by the author. Please contact the author for information regarding the reproduction and use of this thesis or dissertation.

School	Rollins School of Public Health
Department	Epidemiology
Degree	M.P.H.
Submission	Master's Thesis
Language	English
Research Field	Health Sciences, Epidemiology Health Sciences, Public Health
关键词	COVID-19
Committee Chair / Thesis Advisor	Aaron Siegler, Emory University

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