The effect of ambient air pollution on term birth weight and preterm birth in Kansas, 2005-2013 公开
Yoo, Sodahm (Spring 2021)
Abstract
Epidemiologic studies suggest that exposure to ambient air pollution during pregnancy increases the risk of low birth weight and preterm birth; however, the evidence remains inconsistent. We examined the relationship between ambient levels of particulate matter < 2.5 𝜇𝑚 in diameter (PM2.5), PM2.5 chemical constituents [elemental carbon (EC), organic carbon (OC), and nitrate (NO3), ozone (O3) carbon monoxide (CO), nitrogen dioxide (NO2), and nitrogen oxides (NOx) and two birth outcomes, birth weight and preterm birth, between 2005 and 2013 in Kansas. Using a generalized additive modeling framework, we evaluated relationships between birth weight and pollutant concentrations during the first trimester, second trimester, third trimester, and total pregnancy. For preterm birth, we estimated the risk of preterm for both time-invariant and time-variant exposures with a discrete-time survival model. We also studied the potential modifying effect of pre-pregnancy hypertension, pre-pregnancy diabetes, and infant sex. In this statewide analysis, ambient levels of second- trimester PM2.5, second-trimester O3, total-pregnancy O3, and total-pregnancy PM2.5 were significantly associated with reductions in birth weight [-3.6 to -9.6 g per interquartile range (IQR) increase in pollutant concentrations]. Time-varying total pregnancy NO3 was significantly associated with a 5% decreased risk of preterm birth per IQR increase. These findings suggest some support for an effect of ambient air pollution on term birth weight and preterm birth in Kansas.
Table of Contents
I. Introduction
II. Methods
i. Study population
ii. Exposure assessment
iii. Statistical analysis
III. Results
IV. Discussion
V. References
VI. Tables
VII. Figures
VIII. Supplementary Tables
About this Master's Thesis
School | |
---|---|
Department | |
Degree | |
Submission | |
Language |
|
Research Field | |
关键词 | |
Committee Chair / Thesis Advisor | |
Committee Members |
Primary PDF
Thumbnail | Title | Date Uploaded | Actions |
---|---|---|---|
The effect of ambient air pollution on term birth weight and preterm birth in Kansas, 2005-2013 () | 2021-04-26 19:53:27 -0400 |
|
Supplemental Files
Thumbnail | Title | Date Uploaded | Actions |
---|