Prenatal PBDE exposures among African American women living in metropolitan Atlanta: Exposure in home environment 公开
Tsai, Chia Chen (Spring 2019)
Abstract
Dust concentrations of polybrominated diphenyl ethers (PBDEs) collected in households with 34 pregnant African American women living in metropolitan Atlanta area during 20-24 gestational week were measured using gas chromatography mass spectrometry. Demographic and housing characteristic data were collected through home survey questionnaire during home visit. Dust samples were sieved twice to a particle size of less than 150 µm and analyzed for six congeners (PBDE-47, -85, -99, -100, -153, and -154).
Among all commercial mixtures selected in this study, PBDE-47, -85, -99, and -154 were detected in all samples (100%), while PBDE-100 were detected in 28 samples (82.3%) and PBDE-153 were detected in 32 samples (94.1%). Among all selected PBDE congeners, PBDE-99 had the largest geometric mean (380.25) while PBDE-154 had the smallest geometric mean (24.20). In addition, we observed that PBDE-47, -99, and -100 have wider intervals among all 34 samples. Income level had a significant association with PBDE-85, while birth outcome shown significant association with PBDE-47, -85, -153, and -154.
Also, there are associations between housing characteristics and PBDE exposure. To be more precise, there was association between type of household and PBDE-85, -153, and -154; identification of paint chips or dust from paint and PBDE-47, -100; using mops to clean floors and PBDE-47, -85, -99, and -154; using vacuums to clean floors and six of the selected PBDE congeners, shaking the rugs or mats and PBDE-47 and -100; and floor cleaning frequency and PBDE-85 and -153. Results indicate that PBDEs are still detectable in household after the usage prohibition since 2004 in the United States. Dust concentration of PBDES are associate with population and housing characteristics.
Table of Contents
Table of Contents
DISTRIBUTION AGREEMENT 1
BACKGROUND 1
HEALTH EFFECTS. 3
SIGNIFICANCE IN THE SOUTHEAST AS IN AN AFRICAN AMERICAN POPULATION. 4
METHODS 5
STUDY PARTICIPANTS. 5
HOME SURVEY DATA COLLECTION. 6
HOUSEHOLD CHARACTERISTICS. 6
HOUSEHOLD VACUUM DUST COLLECTION 6
PBDE EXPOSURE. 7
QUALITY CONTROL. 9
STATISTICAL ANALYSIS. 9
RESULTS 10
CHARACTERISTICS OF THE STUDY POPULATION AND HOUSEHOLDS. 10
PBDE DETECTION AND CONCENTRATION IN DUST SAMPLES. 11
ASSOCIATIONS WITH PBDE EXPOSURES. 12
DISCUSSION 13
CONCLUSIONS 15
REFERENCE 17
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