The association between family history of diabetes and vision impairment in the US population Open Access
Gao, Weiqing (2010)
Abstract
Abstract
The association between family history of diabetes and vision
impairment in the US population
By Weiqing Gao
Objective: To study the association between familial risk of
diabetes and the prevalence of uncorrectable vision impairment
among adults living in the US.
Research design and Methods: The sample analyzed is from a
cross sectional, nationally representative survey of the US
population (1999-2004 National Health and Nutrition Examination
Survey, NHANES, n=12,742). Diabetes was defined as diagnosed (the
participant acknowledged receiving a diagnosis of diabetes from a
health professional) and previously undiagnosed (a fasting glucose
≥ 126 mg/dl detected during the survey). Familial risks were
classified as average, moderate and high. Uncorrectable vision
impairment was defined as visual acuity worse than 20/40 in the
better seeing eye after an objective autorefraction test.
Prevalence and odds ratio of uncorrectable vision impairment were
estimated for each familial risk class after controlling for key
covariates.
Results: The crude prevalence of uncorrectable vision
impairment for each familial risk class was 1.1%, 1.1% and 1.3%
respectively. There was a statistically significant association
between familial risks of diabetes and uncorrectable vision
impairment even after controlling for sex, age, race/ethnicity,
education, smoking, BMI, hypertension, hypercholesterolemia and
duration of diabetes. The odds of having uncorrectable vision
impairment for people at moderate or high family risk, compared
with people at average familial risk, was 2.29 (95%CI, 1.02-5.14),
independently of all other covariates.
Conclusions: In a nationally representative sample of the US
adult population with diabetes, family history of diabetes was
significantly and independently associated with the prevalence of
uncorrectable vision impairment.
The association between family history of diabetes and vision
impairment in the US population
By
Weiqing Gao
M.D
China Medical University
Thesis Committee Chair: Muin J. Khoury, MD. PhD.
A thesis submitted to the Faculty of the
Rollins School of Public Health of Emory University
in partial fulfillment of the requirements for the degree of
Master of Public Health
in Epidemiology
2010
Table of Contents
TABLE OF CONTENTS
Abstract...1
Table of Content...3
Introduction...4
Literature Review...8
Methods...13
Results...18
Discussion...22
Reference...26
Tables...35
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