Grant proposal to study the effects of dietary modifications in pre-hypertensive African-Americans aged 18-35. Open Access

Sattar, Sobia (2017)

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According to the Centers for Disease Control and Prevention (CDC), African Americans develop high blood pressure at a younger age and more often than any other ethnicity. Complications of High blood pressure can prove debilitating and range from blindness, kidney diseases and stroke, as well as putting an individual at risk for other illnesses such as diabetes and heart disease. Pertinent to this fact, is the high incidence of cardiovascular disease among African Americans compared to other races. The disproportionately high rate of hypertension among blacks poses a unique challenge for researchers to explore race-specific guidelines targeting social, economic or environmental or habitual factors, which can help prevent the onset of hypertension in these individuals. This grant proposal seeks to identify the consequences of differential dietary habits and aims to seek any correlation between a modified diet regimen and incidence of high blood pressure among African Americans aged 18-35.

By using a quasi-experimental two group pre-post design, we will examine whether patients who are pre-hypertensive that receive standard prevention guidelines plus dietary based interventions will show improvements in clinical and patient reported outcomes versus a control group receiving only standard prevention guidelines and no dietary advice. The population selection will be based on the criteria of being African American and between the ages of 18-35 residing in the Greater Atlanta area with documented pre-hypertensive readings with a systolic pressure from 120 to 139 mm Hg or a diastolic pressure from 80 to 89 mm Hg at least 3 times in the past 6 months.

Table of Contents

Table of Contents

Chapter I: Introduction

Introduction and Rational

Problem Statement

Purpose Statement

Significance Statement

Chapter II: Review of the Literature


The Disease Burden

Hypertension among African-Americans

Diet affects Blood Pressure

Chapter III: Methodology

Funding Agency - American Heart Association

Grant Announcement

Grant Proposal Reviewers

Protection of Human Subjects

Chapter IV: Incorporation of Reviewer Comments

Reviewer 1 Comments

Reviewer 2 Comments

Reviewer 3 Comments

Reviewer 4 Comments

Reviewer 5 Comments

Chapter V: Grant Proposal

Specific Aims

Background and Significance

Preliminary Studies

Research Design and Methods

Ethical Aspects of the Proposed Research

Biographical Sketch

AHA Research Project Environment



Appendix A: Assent and Consent Form

Appendix B: Health Insurance Portability and Accountability Act Of 1996.

Appendix C: General Health Pre-Screening Form

Appendix D: Logic Model

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