Caregiver distress and medication errors in pediatric leukemia maintenance therapy Open Access

Stacks, Samantha (Fall 2018)

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Background and Objective: Caregivers of children with chronic illness are predisposed to increased levels of distress due to many factors including the complex nature of medication management. Our objective was to assess the relationship between caregiver distress and medication administration errors in the home in pediatric leukemia patients.

Methods: Using baseline data from participants in a prospective observational study on factors leading to medication error and injury in pediatric leukemia patients in maintenance therapy, a multivariate Poisson regression model was created to analyze the relationship between caregiver distress and the number of medication administration errors that occurred.

Results: In 34 patients, 64.71% committed at least one medication administration error and 17.65% of caregivers were categorized as distressed. Patients with more medication errors were prescribed more medications (p=0.05) and were younger in age (p=0.07). Caregiver distress was not found to be significantly associated with number of medication errors (p=0.89).

Conclusions: Medication administration errors in the home may be influenced by child age and number of medications prescribed. A larger sample size and further research is needed to determine the relationship between parental distress and medication error.

Table of Contents

Distribution Agreement                                                                                                              1

Abstract                                                                                                                                          4

Acknowledgements                                                                                                                      6

Introduction                                                                                                                                  8

Methods                                                                                                                                   14

Results                                                                                                                                          20

Discussion                                                                                                                                  23

Limitations                                                                                                                             26

Conclusions                                                                                                                                 27

Appendices                                                                                                                                  28

References                                                                                                                                   34

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