Identifying Gaps in the Zoonotic Disease Burden of Central America Open Access

Taylor, Megan (Spring 2022)

Permanent URL:


Background: CDC’s One Health Zoonotic Disease Prioritization (OHZDP) Process brings together representatives from human, animal, and environmental health sectors to prioritize zoonotic diseases of greatest concern and to develop next steps to address these priorities. To prepare for these prioritizations, CDC’s One Health Office maintains a global zoonotic disease burden database and is developing regional zoonotic disease burden databases to support locations conducting OHZDP workshops to have readily available data on zoonotic diseases and identify gaps in zoonotic disease burden in their region.

Objectives: The goal of this project was to develop a regional zoonotic disease burden database for Central America for use during CDC’s OHZDP Process and to identify gaps in the zoonotic disease burden across Central America.

Methods: A list of zoonotic diseases was created by collating zoonotic disease lists from previous OHZDP workshops, along with reviewing recent zoonotic disease literature for Central America in PubMed and Scopus. CDC’s One Health Office’s Excel-based global zoonotic disease burden database was adapted for Central America. A structured data and literature review were conducted for zoonotic disease impacts on humans and animals in the region. Information collected, including data gaps, was assessed, and summarized and profiles for each country in the region were developed.

Results: The database included data on 45 zoonotic diseases in Central America. Data was identified for 387 of 2,160 cells (18%). Most data were found from GIDEON, PAHO, ProMed and GHDx. Human prevalence and incidence data made up most of the database, along with human mortality data.

Discussion: Due to the lack of data identified publicly, it was difficult to assess the zoonotic disease burden across the Central America region. Human surveillance data for some zoonotic diseases are being published publicly on a routine basis; however, there was limited information publicly available on the animal health side. To effectively prepare for OHZDP workshops in the region, it is imperative to collaborate with human, animal, and environmental health ministries to incorporate additional data into these databases for a more complete assessment of zoonotic disease burden in the region.

Table of Contents

1. Introduction

Zoonotic Disease Overview 1-2

Zoonotic Disease Impact 2-3

One Health 3-4

CDC One Health Office 4-5

CDC One Health Zoonotic Disease Prioritization 5-6

Project Purpose 6


2. Methods

Zoonotic Disease Selection 7

Database Development 7

Data and Literature Review 7-9

Sample Search Strings 9-10

Citing Data Available 10

Country Vignettes 10


3. Results

Zoonotic Diseases Included for Central America 10-11

Central America Zoonotic Disease Burden Database 12-16

Literature Searches 17


4. Discussion

Discussion of Results 17-21

Recommendations 21-22

Future of One Health in Central America 22


References 23-26


Appendix 27-29

About this Master's Thesis

Rights statement
  • Permission granted by the author to include this thesis or dissertation in this repository. All rights reserved by the author. Please contact the author for information regarding the reproduction and use of this thesis or dissertation.
  • English
Research Field
Committee Chair / Thesis Advisor
Committee Members
Last modified

Primary PDF

Supplemental Files