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Ancestral Sequence Reconstruction as a Lead Optimization Approach in Gene Therapy Drug Development
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Discovery of Novel Natural Products to Combat Multidrug Resistant Bacteria and Fungi
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Botanicals As A Source Of Novel Therapeutics For Infectious Diseases
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Elucidating the Lysosomal Function of Granulins
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Streamlined Approach to Identify Novel Immunomodulatory Agents to Mitigate Ischemic Stroke in a Primary Microglia Model
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Determining the impact of the RGS14-Gαi1-GDP complex on NHERF1 binding
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Development of a Targeted Identification Platform of Small Molecule Inhibitors for Rare and Orphan Diseases
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GluN2B-Selective NMDA Receptor Negative Allosteric Modulation as a Treatment for Chronic Pain and Opioid Tolerance
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Studies in Small Molecule Drug Discovery: Part I. Synthesis of Novel Nucleoside-Based Antivirals to Treat Hepatitis C; Part II. Validation and Implementation of a Machine Learning Algorithm to Create a Safer Kinase Inhibitor as a Potential First-in-Class Antiparkinsonian Agent
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Investigating the therapeutic role of EP2 antagonism in two-hit mouse model of Alzheimer’s disease
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Pharmacological analysis of liver-directed AAV-fVIII gene therapy and anti-fVIII inhibitor incidence in a preclinical model of hemophilia A
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Morse Fall Scale Score Impact on Administration of Benzodiazepines and Opioids
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The impact of rare human genetic variants and disease-linked mutations of RGS14 on the RGS14-Rap2A interactions and the regulation of JNK signaling
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Linezolid Use and Cytopenias in Patients Treated for Multidrug-resistant Tuberculosis
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Development of a novel antibiotic adjuvant strategy against hypervirulent Community-Associated Methicillin-Resistant Staphylococcus aureus
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Inhibiting VIP Receptor Signaling Promotes T Cell Mediated Immune Response in Murine Melanoma Models
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Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells
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Synthesis, Structure-Activity Relationship, and Biological Evaluation of Subunit-Selective NMDA Receptor Modulators
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Gut microbiome product delta-valerobetaine controls host metabolism
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Abnormal Recovery from Anesthesia: A Marker of Early Cognitive Dysfunction in Rodent Models of Disease
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