The Dynamics and Kinetics of Proton Related Biological Processes

Engineering the Regioselectivity of Cyclododecanone Monooxygenase

Prion Delivery via Peptide-Nucleic Acid Co-assembly: the Inside-out Virus

Size Dependence of Gold Nanoparticles – How Site-Specific Conjugation to Dihydrofolate Reductase Alters Characteristics

Kinetic Studies of Rhodium(III)-Catalyzed Allylic C-H Amination of Disubstituted Olefins

Engineering the Stereospecificity and Regioselectivity of Flavoenzymes

BACTERIAL LIPIDS INDUCED AMYLOID ASSEMBLY AND DISEASE ETIOLOGY

Electronic Structure of Metal-Containing Diatomic Ions

Engineering Self-Assembling Peptide Systems

Engineering Advanced Self-Assembling Protein Biomaterials through the Extrapolation and Functionalization of Peptide-Based Systems

Strategies to Develop Antibiotics via Diversification from Natural Products

Chemical Approaches to Elucidate Novel Facets of Nucleic Acid Metabolism and Signaling

Synthesis of septanose glycals and progress towards endo-mode cyclization of polyepoxides

Changes in State: Simulations of Aggregation and Ordering in Finite Systems

Enzyme Dynamics Elucidated via Temperature Jump Fluorescence Spectroscopy

Synthesis of small molecule therapeutics and ligands utilizing rhodium carbenoid chemistry

Amplification of amyloid-beta strains and their connection to tau in Alzheimer’s Disease

Astrochemistry in Star-forming Regions: LaboratoryMillimeter-Submillimeter Spectroscopy and BroadbandAstronomical Line Surveys

Progress toward Lewis acid catalyzed asymmetric transformation of amino alcohols towards influence on the Blakey group synthesis of malagashanine

Photoelectrochemical Studies on a Triad Electrode for Light-driven Water-splitting

Potential Cross-Talk between the Aryl Hydrocarbon Receptor (AHR) and the Constitutive Androstane Receptor (CAR)

Design, Development and Application of a Novel In-Silico High-throughput Screening Approach

COMPARING AND CONTRASTING TWO PLANT PATHOGENS PROVIDE A UNIQUE WINDOW INTO THE DIFFERENCES IN THE INNATE IMMUNE RESPONSES BETWEEN DICOTS AND MONOCOTS

Fast Mixing Reveals Two-state Folding of Apomyoglobin

Investigating the Molecular Complexity of the Interstellar Medium

Development and Application of Synthetic Riboswitches as Tools to Study Bacterial Pathogenesis

SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM CARBENOID CHEMISTRY

Synthesis Towards a Constrained Paclitaxel Analog

Immobilization Methods for Binding Polyoxometalates onto Surfaces for Water Splitting Applications

The Coordination Chemistry of Hydrogen Peroxide

Part I. Design of a novel class of reversible non-covalent small molecule inhibitors for human Granzyme B (hGrB) Part II. Curcumin and mimics as proteasome inhibitors Part III. Design of novel coactivator binding inhibitors (CBIs) for the estrogen receptor α : break the 1µM barrier

Development of Transition Metal Catalyzed Metallonitrene and Metallocarbene Group Transfer Reactions

Synthesis and Excited State Dynamics of Oligothiophene-Nitronyl Nitroxides

Protein-based Tension Probes: From Mapping Integrin Adhesion Forces to the Mechanopharmacology of Smooth Muscle Cells

I: Expanding Genetic Code in S. cevevisiae with an Orthogonal tRNATrp/UCA/ Tryptophanyl tRNA Synthetase Pair II: Synthetic Yeast Prions based on a Non-NQ-rich Amyloidogenic Sequence Derived from the NAC Protein Sequence of α-Synuclein.

Methanol Photodissociation as a Case Study of Complex Interstellar Organic Chemistry

Development of a novel stereo-selective synthetic route towards Pumiliotoxin C, potent neurotoxin, via asymmetric Diels-Alder and sequential protonation-nucleophilic addition as key reaction steps

EXTENDING THE CENTRAL DOGMA: DEVELOPING NOVEL INFORMATIONAL BIOPOLYMERS

Investigating Fundamental Mechanisms of Peptide Insertion into Membranes

Electronic Spectroscopy of Polycyclic Aromatic Hydrocarbons (PAHs) and Group IIA Metallic Oxides

Charge Transfer Dynamics in Homogeneous and Heterogeneous Artificial Photosynthetic Systems

Synthesis of 3-Methyl-TpMo(CO)2(5-Oxo-Pyranyl) Organometallic Scaffold and Its Application in Forming Quaternary Center at a Ring Junction via an Oxidative Annulation-Demetalation Cascade

Fundamental properties and applications of surface confined enzymes in gene regulation and molecular motors

Optimization of Dual-tropic CXCR4/CCR5 HIV-1 Entry Inhibitors and a Market Analysis

Conformational Exchange: A Common Mechanism for Amyloid Assembly

Water Oxidation by the All-Inorganic Homogeneous Catalyst [Co4(H2O)2(α-PW9O34)2]10-: System Optimization, Stability Considerations, and Kinetic Analysis

Characterization of Influenza Hemagglutinin Fusion Peptide and Transmembrane Domain Membrane Insertion

Engineering Asymmetric Peptide Membranes

Charge Separation and Transport Dynamics in One-Dimensional Colloidal Nanostructures for Solar Energy Conversion

Role of Loop Motions in Enzyme Catalysis

Mechanism of Tetrameric Transmembrane Influenza A/M2 Proton Channel Activation

Genetic Engineering of Auxotrophic Saccharomyces boulardii Mutants for Antigen Expression

Towards the Development of Non-Toxic Therapeutics in the Fight Against Cancer

Line tension assisted membrane permeation at the transition temperature in mixed phase lipid bilayers

Theoretical Studies of the Vibrational Spectra and Relaxation Dynamics of Ice and Water

Expanding the scope of donor/acceptor rhodium-carbene chemistry

Synthesis of Naphthalene Diimide-Based Polymers for High Charge Transport

Characterizing the Downregulation of CYP2J2 by Nitric Oxide

Potential Energy Surfaces and the Applications to Reaction Dynamics and Molecular Vibrations

Amyloid: Merging the Properties of Membranes and Enzymes

An Approach to Generate Ultra-Robust and Highly Modular Molecular Tension Probes and Thermo-Responsive Enzymatic Nanoreactors to Regulate Reaction Rate

Synthetic Studies Toward Methanoquinolizidine-Containing Akuammiline Alkaloids

Use of Furans as Vehicles for Heterocyclic Synthesis: An aza-Achmatowicz Approach to Piperidine Alkaloids, a Novel Oxidative Route to Acyloxypyrrolinones, and IMDAF Studies Toward a Synthesis of Minfiensine and Morphine

Investigations of exo-Mode Oxacyclizations for the Synthesis of Cyclic Ethers

Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the Treatment of Hepatitis C Virus

EXPANDING THE SCOPE OF REACTIONS AND APPLICATIONS OF DONOR/ACCEPTOR METALLOCARBENES

Development and Applications of Orthogonality Constrained Density Functional Theory for the Accurate Simulation of X-Ray Absorption Spectroscopy

From Amyloid to Copper Arrays: The design of a functional Metalloamyloid Nanostructure (MAN)

Exo-mode oxacyclization strategies for synthesis of trans-fused polycyclic ethers: the ABC ring sector of brevenal

Semiconductor Nanoparticle-Protein Hybrid Systems for Solar Hydrogen Production and Photo-Triggered Mechanistic Studies

Heterogeneity in fast-folding beta proteins

Photoelectron Velocity Map Imaging Spectroscopy of Small Beryllium-Containing Anions

Semiconductor Nanomaterials in Photocatalytic Bipyridine Reduction and H2 Generation

Design and Development of Novel Bis(amidophenyl)amine Redox-active Ligands to Promote Novel Reactivity at First-row Transition Metal Centers

Cobalt-substituted Polyoxometalates as Viable WaterOxidation Catalysts

Proton, Electron and Proton-coupled Electron Transfer Dynamics in the Catalytic Mechanism of [NiFe] and [FeFe] Hydrogenases

Metallonitrene/Alkyne Cascade Reactions: Development of a Versatile Process for Organic Synthesis

I. Organometallic Enantiomeric Scaffolding: Total Synthesis of (-)-Adaline and (-)-Adalinine Using a Key 5-Oxo-Pyridinyl Molybdenum Scaffold and Featuring a Semipinacol Rearrangment/1,5-"Michael-like" Sequence. II. Exchange Reactions of 1-Alkoxy and 1-Sulfonyloxy 3-Allyl Molybdenum Complexes

Conditional Deoxyribozyme Gene Knockdown: Investigating DNA Displacement Reactions on Gold Nanoparticles

Improving a Synthetic Riboswitch that Responds to an Herbicide

Incorporating Transition Metal Organometallic Chemistry into the Introductory Organic Chemistry Course

Interfacial Electron Transfer Dynamics from Single Molecules and Quantum Dots Studied by Single-Molecule Fluorescence Spectroscopy

Asymmetric Synthesis of 8-oxabicyclo[3.2.1]octane Derivatives Using a Chiral Dirhodium Catalyst

Synthesis, Characterization, and Dioxygen Reactivity of a Copper(I) Complex Supported by a Tripodal Tetraamine Ligand

Dynamics of Influenza Virus Hemagglutinin Fusion Peptide Membrane Insertion

Engineering The Substrate Specificity Of Human Deoxycytidine Kinase

Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone Analogs Part II: Discovery of Small Molecule CXCR4 Antagonists

Fluorescence Studies of Polystyrene in Polystyrene/Poly(vinyl methyl ether) Blends and Multilayers Thesis

Elasticity and Structure of Self-Assembled Systems with Defects and Inclusions

Computer-Assisted Drug Discovery Part I: Design, Development, Validation and Application of FRESH, a Novel In-Silico High-throughput Screening Program Part II: Monocarbonyl Curcumin Analogues: Heterocyclic Pleiotropic Kinase Inhibitors that Mediate Anticancer Properties Part III: Development of 2nd Generation NAMFIS Software Program by Java

Enantiomeric Scaffolds. Molybdenum Pyranyl π-Complexes for the Asymmetric Construction of Oxa-Heterocycles

Elucidating the Biophysical Mechanisms of Notch Activation

Synthetic Studies Towards the Total Synthesis of Myrtoidine

A menthol derived synthon for preparing homoallylic alcohols bearing three contiguous elements of stereochemistry and Progress towards a synthon with two centers of reactivity for the allylation of two different aldehydes

Engineering Candida antarctica lipase B by circular permutation and incremental truncation

Engineering kinases for dual thymidine and thymidylate kinase activity

Transition-metal-substituted polyoxometalates as water oxidation catalysts

Design, Synthesis and Biological Evaluation of C4-C9 Bridged Epothilone Analogs

Impact of Silyl Ethyl Esters on the Rhodium(II)-Catalyzed Transformations of Donor/Acceptor Carbenes