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(Frame)shifty Business: Disruption of Ribosome Fidelity to Subvert the Genetic Code
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Leveraging force-triggered biomolecular interactions to study T cell function
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Bioinspired C(sp2)-C(sp3) Cross-Coupling Strategy Toward the Synthesis of RiPP Natural Product Derivatives and Development of a One Carbon Linchpin for Rh(III)-Catalyzed and Carbon-Directed C–H Annulation
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Spectroscopic Probes of Electronic States in Strongly Correlated Materials and Unconventional Superconductors
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Direct Vibrational Probe of Energetics at Semiconductor/Electrolyte Interface
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In Silico Rationalization of Progesterone Prodrugs’ Self-Immolation Rate
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Copper catalyzed C-O cross-coupling synthesis of structurally complex vinylic ethers: enabling technology for the non-traditional synthesis of various glycosides
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Novel tools for mapping molecular scale cell-generated forces
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Developments in the Synthesis and Methodology of Planar Chiral Rhodium(III) Indenyl Catalysts
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Lipid Logic: Decoding the Mechanism and Kinetics of Tenofovir Lipid Prodrug Cellular Uptake to Improve Efficacy and Safety in HIV Treatment
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Chemical Tools to Combat Antibiotic Resistance: Design, Synthesis, and Biological Evaluation of Antibiotic Natural Products and Adjuvants
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Development of a Variable Soluble Protein Detector with Cas12a Amplification
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Investigating the Role of JAK/STAT as a Potential Pharmacological Target for Epilepsy
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Construction of a Nickel Catalyst Library (NiCL) for Informed High-Throughput Experimentation (I-HTE)
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Creation of an Iron Catalyst Library using Thermogravimetric Analysis for Informed Reaction Development
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Spectral Measures of Quantum Chaos and Wavefunction Delocalization in Photonic Wires
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Lipid-associated macrophages promote Osimertinib resistance in Non-small cell lung cancer
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Novel Synthesis of an IDO-1 Inhibitor Analog utilizing Photocatalyzed Spirocyclization and Rhodium Catalyzed Stereoselective C–H Functionalization
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Isolation and Characterization of an Anti-Acne Compound from Callicarpa americana L. Leaves
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A Computational Exploration of Dynamic Protein Systems: From Metal-Amyloid Interactions to Synthetic Collagen Structures
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TEM characterization of helical amyloid filaments in Alzheimer’s disease human brain comparing disease progression rates
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Coordination of Cyclic (Alkyl)(Amino) Carbenes to an Iron Center Through Use of Internal Bases
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A Bioinformatic Approach towards Tuning Specific Halogenating Activity of Vanadium Haloperoxidase Enzymes
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Activity and Structural Analysis of K. aerogenes Urease Utilizing X-ray and UV-vis Spectroscopy
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Exploring the Mechanistic Implications of Pseudomonas aeruginosa Antimicrobial Resistance
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Evaluating the Therapeutic Potential of Micro-fragmented Adipose Tissue in the Treatment of Partial-Thickness Rotator Cuff Tears
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Progress Toward Synthesis and Characterization of an NHC–Aryl Chelated Bismuth Complex
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Development of Enantioselective Hantzsch Ester Synthesis for Drug Repurposing Applications
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CdSe 9-ACA DPA Solid Polymer Host for Green-Blue Triplet-Triplet Annihilation Upconversion
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Purification of THEMIS2 Protein Domains
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Leveraging Chylomicron-Mediated Transport to Advance Long-Acting Oral HIV Therapeutics
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Structural Basis of R-Loop Mediated cGAS Activation
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Reduction of Alkenes and Heterocycles via Photochemical Activation of Formate
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Advances Toward P(V) Reagents for Phosphorylation: Synthesis and Characterization of Three Novel P(V)–NHC Compounds
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Synthesis of the variant of Phenyl Adamantyl Dirhodium (II) Tetracarboxylate Catalyst via Palladium-catalyzed Suzuki-Miyaura Cross-Coupling
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Chemical Methods for Arginine Modification in Peptides and Proteins
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Synthetic Platforms for Accessing Tag-free Macrocyclic Peptides
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Biochemical Investigation of Glucocorticoid Receptor Ligand Binding Domain in Complex with Methylprednisolone
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Mechanism of OAS1 Activation by a Conserved SARS-CoV-2 Region
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Chemical Strategies for Labeling and Profiling 1-Methyl Histidine Post-Translational Modification and Lysine Functionalization
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Selective Conversion of C-terminal Amides to Nitriles for Reagent Free Synthesis of Bioactive Cyclic Peptides
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Progress Towards the Syntheses of Ribosomally Synthesized and Post-Translationally Modified Peptide Natural Products
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The Role of Radical SAM Enzymes in Biochemical Pathways: A Focus on Methyltransferases and RiPP-Modifying Enzymes
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Navigating the intricacies of the molecular structure-function relationship at the interface of chemistry, biology, and physics
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Controlling Selectivity in 5-exo and 6-endo Radical Cyclizations
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Correlations Between Dietary Macronutrient Intake and the Gut Microbiome in Adults Undergoing Bariatric Surgery for Obesity
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Controlling Carbenes: Stories of Diruthenium, Dirhodium, and Photoinduced Carbene Transformations
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Leveraging Catalysis to Enable the Asymmetric Synthesis of Novel Cereblon E3 Ligase Modulatory Drug Cores
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Natural Product-Inspired Strategies to Address Antibiotic Resistance in Pseudomonas aeruginosa
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Photoactive compounds for time-resolved spectroscopic analysis of heme-dependent metalloenzymes
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Antibacterial Activity and Chemical Composition Analysis of Ruta graveolens L. Leaves and Stems Extract
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Synthesis of Novel Nucleotide Tenofovir/Lamivudine Prodrug Conjugates for treatment of Human Immunodeficiency Virus and Hepatitis B
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Expanding The Scope of Reactions and Applications for Dirhodium(II) Tetracarboxylate Catalyzed Carbene Reactions Toward C–H Insertion and Cyclopropanation.
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Radical Chain Reduction and C(sp2/sp3) Carboxylation via Formate Activation
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Exploring Enigmatic Enzymatic Reactivity: Structural Insights into Natural Product Biosynthesis
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Unveiling Lipid Nanodisc DNA Conjugate Uptake: Cell Pathways & Efficiency
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Total Synthesis of Larikaempferic Acid Methyl Ester
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Spectroscopic studies and control of charge carrier dynamics in semiconductor nanocrystals
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Combating Antibacterial Resistance through Novel Cationic Biocides
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Synthesis and Characterization of Novel CXCR4 Antagonist Analogs
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Fibrinogen and Clotting Characterization in COVID-19 Patients
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Expanding the Toolbox: Development of Novel Chemical Tools for Profiling of Proteins and Dimethyl Post-translational Modification
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Development of Enantioselective C–N Bond Forming Reactions using Planar Chiral Rh(III) Indenyl Catalysts
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Self-assemblies of electrostatically self-complementary peptides derived from different structural motifs
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Modification of Native Biomolecular Functions to Identify and Control Adenosine-to-Inosine Editing of RNA Substrates
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The Big Dissertation on Small Beryllium Clusters
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Systems Chemistry of Self-Replicating Networks: From Nature to Nanomaterials
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Towards Ideal Synthesis: Concise Total Syntheses of Sesquiterpene and Diterpene Natural Products
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Diagnostic Tools: Molecular Probes for the Detection of Biological Aldehydes
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Hierarchical Self-assembly of Novel DNA Nanostructures for Biomedical and Biomimetic Research
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The Development of VIP Antagonist (ANT) Peptide Derivatives and Synthetic Approaches towards the Ryptide Macrocycle
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Mechanism of Type II Ribosome-dependent Toxin Target Selection
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Investigating Lithium Enrichment in Infrared Excess K-G Giants
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A Study of the Effect of Amino Acid Substitutions on Cannula Mimetic Proteins
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Development, Characterization, and Corresponding Reactivity of First-Row Transition Metal Complexes with Redox-Active Catecholamine Ligands
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Designing a Library of Conjugated Planar Chiral Rh(III) Indenyl Catalysts and Progress Towards an Enantioselective Intramolecular 1,2-Arylamination of Terminal Olefins using Planar Chiral Rh(III) Indenyl Catalysts
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Optimization and Investigation of a Photoredox-Driven Selective Radical Cyclization
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Understanding the Reactivity of Planar Chiral Naphthindenyl Rhodium(III) Catalysts
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The Mutational, Environmental and Immunological Drivers of Leukemia Resistance
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Pharmacological Regulation of Macrophage Polarization
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Seeding of synthetic amyloid-β(1-42) monomers by amyloid-β(1-42) present in Alzheimer’s brains
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Six Amino Acids: Accessing OAS1 Inhibitors
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Exploring the Urease Mechanism by Light Driven Uncaging of Urea Compounds
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Copper Catalyzed Lipid Polysaccharide Monooxygenase Biomimicry of Polysaccharide Oxidative Cleavage
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Identification of IgG1 Fc mutations affecting enzymatic inactivation by IdeS via deep mutational scanning
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Synthesis of P1 and Cap-P2 Fragments of Novel SARS-CoV-2 Protease Inhibitors
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Total Synthesis and Target Identification of Pestalachloride B to Facilitate Antibiotic Development
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Safety and Efficacy Demonstrated in Chemogenetic Application of CODA Viral Transgene in Modulating the Motor Activity of Rats
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Synthetic Investigations Into the Diterpenoids Larikaempferic Methyl Ester and (-)-Hardwickiic Acid
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The Stereochemical Effect of HFIP on Asymmetric Rhodium(II)-Catalyzed Cyclopropanation
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Synthesis of Lipid Prodrugs of Tenofovir to Promote Lymphatic Uptake and Combat Toxicity
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Mechanism and Evolution of tRNA CCA-adding Enzymes
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Computational Discovery of Inhibitors for the Oncogenic Protein MKK3
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Synergistic Paradigm of Radiotherapy and PD-L1 Blockade Orchestrates the Induction of Stem-Like T Cell Populations within the Tumor-Draining Lymph Node
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Bioinspired Chemical Approach for Synthesis of Allysine
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Urinary RNA Biomarkers in Extracellular Vesicles from Post-DRE Urine to Predict Aggressive Prostate Cancer
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Structure-Activity Relationship Studies of EP2 Antagonists for Aqueous Solubility Enhancement
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Biofilms on a Bead: A Novel Model System to Probe Plant-Microbe Interactions
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Fighting the Good Fight: Structure Based Design and Biological Investigation of Allosteric OAS1 Inhibitors for Mitigating Inborn Errors of Immunity
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Synthesis, Structure-Activity Relationship, and Biological Evaluation of Subunit-Selective NMDA Receptor Modulators
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