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The Design, Synthesis, and Biological Evaluation of Novel Prodrugs and Antiviral Agents for HIV and Other Chronic Viral Infections
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Site-selective and Stereoselective Functionalization of Non-Activated C–H Bond
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Engineering the Stereospecificity and Regioselectivity of Flavoenzymes
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Mechanistic Study on Multi-Electron Processes in POM Catalysis
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Structure-Activity Relationship and Quantitative Structure-Activity Relationship of GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor
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Natural and Synthetic Compounds as Tools to Overcome Antibiotic Resistance
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Amplification of amyloid-beta strains and their connection to tau in Alzheimer’s Disease
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The Dynamics and Kinetics of Proton Related Biological Processes
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Synthesis of small molecule therapeutics and ligands utilizing rhodium carbenoid chemistry
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Enzyme Dynamics Elucidated via Temperature Jump Fluorescence Spectroscopy
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Changes in State: Simulations of Aggregation and Ordering in Finite Systems
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Chemical Approaches to Elucidate Novel Facets of Nucleic Acid Metabolism and Signaling
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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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Cross-ß Folds of Amyloid as a Versatile Self-Propagating Catalyst
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SYNTHETIC AND QUANTUM-CHEMICAL EXPLORATION OF THE SELECTIVITY OF
DONOR/ACCEPTOR-SUBSTITUTED METALLOCARBENOIDS
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Part 1: Synthesis and Anti-HIV Activity of Novel CyclobutylNucleoside and Nucleotide Analogs, Part 2: Synthesis of FluorescentNucleoside Analogs, Part 3: Synthesis of Abacavir
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Single Molecule Study of Fluorescence from Organic Dyes at Interfaces
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Metastable Phases Direct Polymer Emergence and Evolution in Dynamic Chemical Networks
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Synthetic Studies for Heterocycle Synthesis Part I:
Intra/intermolecular Olefin Diamination for the Stereoselective
Synthesis of 3-Aminopiperidines Part II: Total Synthesis of
Malagashanine and Synthetic Studies Toward Related Alkaloids
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Development of Microfluidic Mixing Techniques to study Enzymatic Reactions
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Data-Driven Engineering of Therapeutic Enzymes
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Comparative Structural and Functional Properties of Human and Rat Monoamine Oxidases
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Controlling the Synthesis of New Polyoxometalates and RemovingTheir Crystallographic Disorder
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Ligand Design Strategies for Regulating Small Molecule Binding and
Reactivity at Transition Metal Centers
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Expanding the Scope of Donor/Acceptor Rhodium-Carbene Chemistry
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Design, Synthesis, and Utilization of Iridium(III)
Bis(oxazolinyl)phenyl and Iridium(III) Bis(imidazolinyl)phenyl
Complexes for Catalytic Enantioselective Atom Transfer C-H
Functionalization
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TRANSITION METAL CATALYZED STEREOSELECTIVE TRANSFORMATIONS OF
ALKYNES AND DONOR/ACCEPTOR CARBENOIDS
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I. Self-Assembly of Thioether-Modified Cationic Surfactants
II. Electrostatic Binding among Equilibrating 2-D and 3-D
Self-Assemblies
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Analysis of Cocaine Binding Site of Human DopamineTransporter Using Affinity Labeling and MassSpectrometry
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EXPLORATION OF HIGH SYMMETRY DIRHODIUM CATALYSTS AND THE REACTION
OF DONOR/ACCEPTOR CARBENOIDS WITH ALCOHOLS
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Design, Synthesis, and Biological Evaluation of Subunit
Selective N-Methyl-D-Aspartate Receptor Modulators
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Chapter 1. Total synthesis of Fumonisin B1 Chapter 2.
Synthesis of Unnatural Sphingolipids: 1-deoxy-5-hydroxysphinganine
and its diastereomers Chapter 3. Development of Methodology:
Synthesis of cis- and trans-homoallylic alcohols
Chapter 4. Human Milk Oligosaccharides: Synthesis of Natural and
Unnatural oligomers
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Directed Evolution and Computational Design of Nucleoside Analog
Kinases
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Development of Nanoparticle-based Tools to Investigate Cell Mechanotransduction at the Living/Nonliving Interface
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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I. Development of a passive sampler and static sampling chamber
to measure personal exposure to gaseous PAHs. II. Method
development for determination of current-use and persistent
pesticides in cow milk, human breast milk, baby formulas, and human
serum using gas chromatography tandem mass spectrometry.
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Late Transition Metal Oxo Complexes. The Use of Polyoxometalate as a Stabilizing Ligand
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Concise Total Synthesis of (-)-D-erythro-Sphingosine and Sphingosine-1-Phosphate
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Copper-Catalyzed C-N Bond Formation from Ketoxime O-Carboxylates and Application to Pyridine Synthesis
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Desulfitative Coupling Reactions for the Mild Construction of Carbon-Carbon, Carbon-Nitrogen, and Carbon-Oxygen Bonds
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Towards the Synthesis of Marine Polyether Triterpenes
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Biomaterials Design: Creation of a novel orthogonal translationalsystem in E. coli for the site-specific incorporation ofproline analogues in biosynthetic protein materials
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Orientation and Vibrational Dynamics of Rhenium Bipyridyl
CO2-Reduction Catalysts on Model Electrode
Surfaces
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Charge Separation in Polyoxometalate-Based Systems for Solar Energy Production
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Signal Perception and Transmission through the VirA/VirG Two-Component System in Agrobacterium Tumefaciens
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Simulations of Lipid Sorting Effects near Transmembrane
Peptide
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Developing Oxidation Catalysts, Understanding Mechanisms ofPolyoxometalate-based Oxidations, and Systems for Color-ChangeDetection Technology
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Synthesis of protein-based polymers with the potential to form
physically and covalently cross-linked networks
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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A Type-II Thymidine Kinase from Thermotoga maritima: KineticCharacterization, Substrate Binding, and Oligomerization
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Coordination Mode Versatility and Intramolecular Bond Activation
in Metal Complexes Supported by a Family of Tris(amidato)amine
Ligands
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Degradation of pesticides in food and beverages: Implications for
risk assessment
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Amyloid Conformational Diversity Accessed By Truncations of a
Native Protein Fold
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Influence of Arginine 355 and Glutamate 758 on the Substrate Specificities and Catalytic Properties of C. acidovorans Xanthine Dehydrogenase
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Photolabeling of the Human Dopamine Transporter and theReactivity of Aryl Azides with Amino Acid Analogs
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Semagenesis & Xenognosis: Translating the Molecular Dialogues of Host-Parasite Interactions
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Energetic Contribution of Amyloid Self-assembly
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Photoinduced Electron Transfer (ET) Dynamics between MolecularAdsorbates and Semiconductor Nanoparticles with Insulating MetalOxide Overlayers
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Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of
Novel Therapeutic Agents for Cocaine Abuse
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Exploring the peptide nanotube formation from the self-assembly of the Aβ(13-21)K16A peptide in the presence of Zinc ions
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Reaction Dynamics and Vibrational Studies of Atmospheric Species on Potential Energy Surfaces
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Development of DNA-based Fluorescent Molecular Tension Probes to Investigate Integrin Mediated Mechanical Forces
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Modular Synthesis of Polyketide Natural Products: Synthesis of
the C9-C27 Degradation Product of Aflastatin A and Total Synthesis
of Fostriecin
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Quantum Confined Semiconductor Nanocrystals for Efficient Charge
Separation and Solar-to-fuel Conversion
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Biosynthesis and characterization of novel elastin-basedbiomaterials and theoretical calculation of proline analogues
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Development of a Copper Catalyzed Aminoacetoxylation Reaction of
Olefins, Development of an Intermolecular and Diastereoselective
Iminium Cascade Reaction and Studies Towards the Synthesis of a
Malagasy Alkaloid
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Quantum Mechnical Study of Molecular Processes: From Gas Phase to Nano Phase
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Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of
Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of
Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition
of HIV Reverse Transcriptase
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Chiral Materials and Water Oxidation Catalysts from
Transition-Metal-Substituted Polyoxometalates
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Stereocontrolled Synthesis of Ketones bearing Stereogenic Centers
by Desulfitative Cross-Coupling of Thiol Esters and Organostannanes
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Dynamics Calculations of Several Atmospheric Reactions on Global
Potential Energy Surfaces
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Chapter 1: The development of a model system for the B-ring of
brevenal and methods for the formation of seven-membered rings.
Chapter 2: Iterative alkyne-epoxide cross-couplings toward the
total synthesis of PM toxin A. Chapter 3: The development of
synthons for 1,3-dimethylallylation of aldehydes.
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Modulating Amyloid Peptide Self-Assembly With Nucleobase Incorporation
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Understanding signal transduction systems in prokaryotes and eukaryotes
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Engineering Control of Gene Expression in Bacteria Using RNA-Small Molecule Interactions
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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
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Enzyme Engineering
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Nanoscale Tools to Expand the Biophysical Understanding of
Epidermal Growth Factor Receptor Function
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Photoaffinity Labeling of the Human Dopamine Transporter UsingCocaine Analogs
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Molecular simulations of lipid systems: Edge stability and structure in pure and mixed bilayers
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Reaction Kinetics of Phenylisothiocyanate with Amino Acid Analogs
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Programmed Self-assembly of Coiled-coil Peptides
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In Situ Kinetic Studies of Reactions Involving Dirhodium(II)
Donor/Acceptor Carbenes
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Investigation of C-H Bond Oxidation Reactions: I. Asymmetric
Amination of C-H Bonds Using Ruthenium(II) Catalysts II.
Investigation of Structural Determinants of Monoamine Oxidase B
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Biological Engineering with Chemical-Sensing MacromolecularSwitches: I. Discovery and Applications of Small-Molecule DependentSynthetic Riboswitches II. A Genetic Toolbox for CreatingReversible Ca 2+ -Sensitive Biomaterials
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Part I: Synthesis of Cyclobutyl Nucleoside and NucleotideAnalogues as HIV-1 Reverse Transcriptase InhibitorsPart II: Improvement of Glycosylation Regioselectivity in PurineNucleoside Analogue SynthesisPart III: Enantioselective Synthesis ofβ-D-Dioxolane-T andβ-D-FDOC
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Organometallic Scaffolding as a Practical Approach toDiversity-Oriented Synthesis: Stereo- and RegiocontrolledSequential Functionalization of Pyranylalkylidene AllylmolybdenumComplexes
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Utilization of a Michael Addition-Dipolar Cycloaddition Cascade Involving 2,3- bis(Phenylsulfonyl)butadiene for Alkaloid Synthesis
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Analytical Methods for Pesticides and their Degradation Products in Soil
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Ab initio Molecular Potential Energy Surface Constructionand Molecular Dynamics Simulation for Small Molecules
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Use of Receptor-Based Drug Design and Applications in the Study
of finding antagonists for MD-2/TLR4, GLP and CXCR4
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Developing Chiral Synthons for Polyketide-Based Natural Product Synthesis via Stereospecific Oxonia-Cope Rearrangement
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The Counter Cation Effect in the Synthesis and SubsequentReactivity of Polyoxometalates
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Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions
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Explorations of Metallocarbene and Metallonitrene Reactive
Intermediate Chemistry for the Development of Synthetically Useful
New Reactions
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Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin
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