Progress toward Lewis acid catalyzed asymmetric transformation of amino alcohols towards influence on the Blakey group synthesis of malagashanine

Synthesis Towards a Constrained Paclitaxel Analog

SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM CARBENOID CHEMISTRY

Synthesis and Excited State Dynamics of Oligothiophene-Nitronyl Nitroxides

Development of Transition Metal Catalyzed Metallonitrene and Metallocarbene Group Transfer Reactions

Development of a novel stereo-selective synthetic route towards Pumiliotoxin C, potent neurotoxin, via asymmetric Diels-Alder and sequential protonation-nucleophilic addition as key reaction steps

Synthesis of 3-Methyl-TpMo(CO)2(5-Oxo-Pyranyl) Organometallic Scaffold and Its Application in Forming Quaternary Center at a Ring Junction via an Oxidative Annulation-Demetalation Cascade

Optimization of Dual-tropic CXCR4/CCR5 HIV-1 Entry Inhibitors and a Market Analysis

Towards the Development of Non-Toxic Therapeutics in the Fight Against Cancer

Expanding the scope of donor/acceptor rhodium-carbene chemistry

Synthetic Studies Toward Methanoquinolizidine-Containing Akuammiline Alkaloids

Exo-mode oxacyclization strategies for synthesis of trans-fused polycyclic ethers: the ABC ring sector of brevenal

Investigations of exo-Mode Oxacyclizations for the Synthesis of Cyclic Ethers

Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the Treatment of Hepatitis C Virus

Use of Furans as Vehicles for Heterocyclic Synthesis: An aza-Achmatowicz Approach to Piperidine Alkaloids, a Novel Oxidative Route to Acyloxypyrrolinones, and IMDAF Studies Toward a Synthesis of Minfiensine and Morphine

Metallonitrene/Alkyne Cascade Reactions: Development of a Versatile Process for Organic Synthesis

I. Organometallic Enantiomeric Scaffolding: Total Synthesis of (-)-Adaline and (-)-Adalinine Using a Key 5-Oxo-Pyridinyl Molybdenum Scaffold and Featuring a Semipinacol Rearrangment/1,5-"Michael-like" Sequence. II. Exchange Reactions of 1-Alkoxy and 1-Sulfonyloxy 3-Allyl Molybdenum Complexes

Incorporating Transition Metal Organometallic Chemistry into the Introductory Organic Chemistry Course

Asymmetric Synthesis of 8-oxabicyclo[3.2.1]octane Derivatives Using a Chiral Dirhodium Catalyst

Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone Analogs Part II: Discovery of Small Molecule CXCR4 Antagonists

Enantiomeric Scaffolds. Molybdenum Pyranyl π-Complexes for the Asymmetric Construction of Oxa-Heterocycles

Synthetic Studies Towards the Total Synthesis of Myrtoidine

A menthol derived synthon for preparing homoallylic alcohols bearing three contiguous elements of stereochemistry and Progress towards a synthon with two centers of reactivity for the allylation of two different aldehydes

Impact of Silyl Ethyl Esters on the Rhodium(II)-Catalyzed Transformations of Donor/Acceptor Carbenes

Design, Synthesis and Biological Evaluation of C4-C9 Bridged Epothilone Analogs

Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis, and Biological Evaluation of a Novel Class of Allosteric Modulators of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and Conformational Analysis of Structurally Similar CXCR4 Antagonists

Development of a Redox-Active Ligand Framework: A Novel Approach towards Reactivity in C−H Functionalization Reactions

Synthesis and Characterization of Organic and Inorganic Compounds with Biological Applications

Ring Chain Isomerism: Ligands for Mediating Two-Electron Reactivity with First-Row Transition Metals

Studies toward the total synthesis of altromycin natural products

CYCLOADDITIONS AND YLIDE CHEMISTRY OF DONOR/ACCEPTOR- SUBSTITUTED CARBENES FROM THERMAL DECOMPOSITION OF ARYLDIAZOCARBONYL COMPOUNDS

[5+2] Cycloadditions to Form Oxobicyclo[3.2.1]octanes

Design and Development of Novel Methods for C-H Functionalization for Amination and C-C Bond Formation

Development of a Novel Cascade Cyclization Reaction and its Application Towards the Total Synthesis of Malagashanine: A Chloroquine Efflux Inhibitor

Application of IMDAF and Rh(II)-Catalyzed Cascade Reactions for Total Synthesis of Natural Products

RHODIUM CATALYZED ASYMMETRIC TRANSFORMATIONS OF VINYLCARBENOIDS

Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Modulators

Synthesis and Characterization of Unusal Amphiphiles Part I. Nonsteroidal Facial Amphiphiles Part II. Diketopiperazine Derived Surfactants

Chiral dirhodium catalysts design, synthesis and application in asymmetric carbenoid transformations and silver-catalysis of vinylogous fluorination

Design, Synthesis, and Biologic Evaluation of Tetrahydroisoquinoline-Based CXCR4 Modulators

Organometallic Enantiomeric Scaffolds in the Synthesis of Alkaloids: I. Homo-SN2´-like Reaction/Annulative Demetallation and the Application in the Synthesis of (+)-Isofebrifugine II. Uncatalyzed Electrophilic C-C Bond Forming Reactions of Pyranyl and Pyridinyl Molybdenum Complexes

ASYMMETRIC REACTIONS OF DONOR/ACCEPTOR RHODIUM CARBENOIDS: FROM FORMAL CYCLOADDITIONS TO C-H INSERTION

Part 1: Stereoselective Synthesis of Quaternary Center Bearing Azetines and β-Amino Acid Derivatives. Part 2: Natural and Enantiomeric Progesterone Analogues for the Treatment of Traumatic Brain Injury

Synthesis of Those Sectors of Saccharomicin A and B Containing Saccharosamine and the Discovery of a Novel 4-H-1,3-Oxazine Synthesis

Computational Studies of Ligand Protein Interactions Part I: The T-Taxol Conformation Part II: Elucidating Interdependent Binding Sites on Tubulin

The Polyoxometalate / NOx / Brx Catalysts for Aerobic Sulfoxidations

Mild Amide and Peptide Constructions by the Condensation of O-Silylthionoesters with Amines and Metal Mediated Cross-Coupling Reactions for Carbon-Carbon Bond Formation

Synthesis and Reactivity of Benzo[1,3,2]dithiazole 1,1-dioxides: Implications in Acylative Redox Dehydration

Progress Toward a Common Intermediate for C1 Modified Enigmols

Synthesis of Ellagic Acid Glycoside Derivatives found in Rubus ulmifolius

Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Antagonists

Practical Enhancement and Applications of Dirhodium Catalyzed Reactions of Donor/Acceptor Carbenes

Exploring Catalytic Properties of Polyoxometalates in Aerobic Decontamination and Water Oxidation

Ambient Temperature Synthesis of High Enantiopurity N-Protected Peptidyl Ketone by Desulfitative Cross Coupling of Peptidyl Thiol Esters and Boronic Acids

Rhodium Alkenylcarbenes: Novel Reactivity and Precursors

Part I: Conformational Analysis of Bioactive Molecules in Solution Part II: Structure-Based Design of Selective Inhibitors of Cyclin-Dependent Kinase 7

Aerobic, Medal Mediated Ketone Synthesis from Thiol Esters and Boronic Acids

Chapter 1. Biomimetic Total Synthesis of ent-Durgamone, ent-Nakorone and ent-Abudinol B Chapter 2. Biomimetic Synthesis of Fused Polypyrans

Part I: Design, Synthesis, and Biological Activity of NMDA Receptor Antagonists Part II: Design and Synthesis of Measles Virus Inhibitors

SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID REACTIONS

Synthesis of Highly Functionalized Pyrroles Using a Dirhodium Catalyst

Synthesis and Characterization of Organic and Inorganic Compounds with Biological and Material Applications

Rhodium(II)-Catalyzed Asymmetric Transformations and Their Applications in The Development of Novel CNS Drug Candidates

Chapter 1. Part 1: Novel Synthesis and Biological Evaluation of 1,5-Linked D-Mannoseptanosides. Part 2: Synthesis of D-Glucoseptanosides Chapter 2. Biomimetic Total Synthesis of the Proposed Structure of ent-Muzitone

I. Addressing the Regioselectivity Problem in Organic Synthesis. II. A-B-A-B-A Block Amphiphiles. Balance between Hydrophilic and Hydrophobic Segmentation.

A Thorough Investigation of the Characteristic Phosphorus Couplings and 31P NMR Analysis in Attempts to Synthesize an Ifosfamide Analog

Progress Toward the Total Synthesis of PM-toxin A And Future Development of Mild Lewis Acid Activated Alkynylation of Epoxides

Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin

Explorations of Metallocarbene and Metallonitrene Reactive Intermediate Chemistry for the Development of Synthetically Useful New Reactions

Metal Mediated Cross-Coupling Reactions for Carbon-Carbon and Carbon-Nitrogen Bonds Formation under Neutral pH Conditions

Developing Chiral Synthons for Polyketide-Based Natural Product Synthesis via Stereospecific Oxonia-Cope Rearrangement

Utilization of a Michael Addition-Dipolar Cycloaddition Cascade Involving 2,3- bis(Phenylsulfonyl)butadiene for Alkaloid Synthesis

Organometallic Scaffolding as a Practical Approach to Diversity-Oriented Synthesis: Stereo- and Regiocontrolled Sequential Functionalization of Pyranylalkylidene Allylmolybdenum Complexes

Part I: Synthesis of Cyclobutyl Nucleoside and Nucleotide Analogues as HIV-1 Reverse Transcriptase Inhibitors Part II: Improvement of Glycosylation Regioselectivity in Purine Nucleoside Analogue Synthesis Part III: Enantioselective Synthesis of β-D-Dioxolane-T and β-D-FDOC

Investigation of C-H Bond Oxidation Reactions: I. Asymmetric Amination of C-H Bonds Using Ruthenium(II) Catalysts II. Investigation of Structural Determinants of Monoamine Oxidase B

In Situ Kinetic Studies of Reactions Involving Dirhodium(II) Donor/Acceptor Carbenes

Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs

Chapter 1: The development of a model system for the B-ring of brevenal and methods for the formation of seven-membered rings. Chapter 2: Iterative alkyne-epoxide cross-couplings toward the total synthesis of PM toxin A. Chapter 3: The development of synthons for 1,3-dimethylallylation of aldehydes.

Stereocontrolled Synthesis of Ketones bearing Stereogenic Centers by Desulfitative Cross-Coupling of Thiol Esters and Organostannanes

Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition of HIV Reverse Transcriptase

Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity

Modular Synthesis of Asymmetric Triazacyclononane Derivatives and Potential Aerobic Copper Oxidation Catalyst Supported by a Bridging Bulky Triazacyclononane

Development of a Copper Catalyzed Aminoacetoxylation Reaction of Olefins, Development of an Intermolecular and Diastereoselective Iminium Cascade Reaction and Studies Towards the Synthesis of a Malagasy Alkaloid

TARGETING MIXED LINEAGE LEUKEMIA AS ANTICANCER THERAPY FOR INFANTILE ACUTE LYMPHOBLASTIC LEUKEMIA THROUGH THE SYNTHESIS OF NOVEL COMPOUNDS

Modular Synthesis of Polyketide Natural Products: Synthesis of the C9-C27 Degradation Product of Aflastatin A and Total Synthesis of Fostriecin

Incorporating the Scientific Contributions of Research Faculty into the Chemical Education of Undergraduate Students at Emory University

A Methodological Study of Enantioselective Dirhodium(II)-Catalyzed Cyclopropanations at Low Catalyst Loadings

Synthesis and Characterization of N-alkyl-3-(2,4-dichlorophenyl)-N-fluoroalkyl-2,5- dimethylpyrazolo[1,5-a]pyrimidin-7-amines as Potential CRF1 Receptor PET Radiotracers

Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of Novel Therapeutic Agents for Cocaine Abuse

Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2

Investigating Sustainable Precious Metal Catalysis: Routine Dirhodium Catalyzed Carbene Reactions with High Yield and Enantioselectivity at Low Loadings

Part I: Synthesis of Cyclobutyl Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1 Reverse Transcriptase Mutant Part II: Synthesis and Evaluation of Truncated Triptolide Analogs to Suppress Chronic Inflammation

Acylative Redox Dehydration of Carboxylic Acids and Benzoisothiazolones in the Synthesis of Thioesters with Triethylphosphite as a Terminal Reductant

Towards the Synthesis of Marine Polyether Triterpenes

Desulfitative Coupling Reactions for the Mild Construction of Carbon-Carbon, Carbon-Nitrogen, and Carbon-Oxygen Bonds

Copper-Catalyzed C-N Bond Formation from Ketoxime O-Carboxylates and Application to Pyridine Synthesis

Concise Total Synthesis of (-)-D-erythro-Sphingosine and Sphingosine-1-Phosphate

The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators

Synthesis, characterization, and biological stabilities of gold(III) di-2-pyridyl and sec-butyl-phenanthroline complexes