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The Design, Synthesis, and Biological Evaluation of Novel Prodrugs and Antiviral Agents for HIV and Other Chronic Viral Infections
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Site-selective and Stereoselective Functionalization of Non-Activated C–H Bond
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Synthesis of septanose glycals and progress towards endo-mode cyclization of polyepoxides
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Structure-Activity Relationship and Quantitative Structure-Activity Relationship of GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor
4 of 100
Structural Factors of Radical-Enhanced Intersystem Crossing of Organic Chromophores
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Kinetic Studies of Rhodium(III)-Catalyzed Allylic C-H Amination of Disubstituted Olefins
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The Development of Dual-Tropic CXCR4/CCR5 HIV-1 Entry Inhibitors
7 of 100
Natural and Synthetic Compounds as Tools to Overcome Antibiotic Resistance
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Synthesis of small molecule therapeutics and ligands utilizing rhodium carbenoid chemistry
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Chemical Approaches to Elucidate Novel Facets of Nucleic Acid Metabolism and Signaling
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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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SYNTHETIC AND QUANTUM-CHEMICAL EXPLORATION OF THE SELECTIVITY OF
DONOR/ACCEPTOR-SUBSTITUTED METALLOCARBENOIDS
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Part 1: Synthesis and Anti-HIV Activity of Novel CyclobutylNucleoside and Nucleotide Analogs, Part 2: Synthesis of FluorescentNucleoside Analogs, Part 3: Synthesis of Abacavir
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Synthetic Studies for Heterocycle Synthesis Part I:
Intra/intermolecular Olefin Diamination for the Stereoselective
Synthesis of 3-Aminopiperidines Part II: Total Synthesis of
Malagashanine and Synthetic Studies Toward Related Alkaloids
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Synthesis of Novel Anti-Cancer Compounds Based on Sphingolipid
Analogs
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Synthesis and Reactivity of Novel Benzoisothiazolone
Organocatalysts for Redox Condensation Reactions
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Expanding the Scope of Donor/Acceptor Rhodium-Carbene Chemistry
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Design, Synthesis, and Utilization of Iridium(III)
Bis(oxazolinyl)phenyl and Iridium(III) Bis(imidazolinyl)phenyl
Complexes for Catalytic Enantioselective Atom Transfer C-H
Functionalization
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TRANSITION METAL CATALYZED STEREOSELECTIVE TRANSFORMATIONS OF
ALKYNES AND DONOR/ACCEPTOR CARBENOIDS
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I. Self-Assembly of Thioether-Modified Cationic Surfactants
II. Electrostatic Binding among Equilibrating 2-D and 3-D
Self-Assemblies
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EXPLORATION OF HIGH SYMMETRY DIRHODIUM CATALYSTS AND THE REACTION
OF DONOR/ACCEPTOR CARBENOIDS WITH ALCOHOLS
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Design, Synthesis, and Biological Evaluation of Subunit
Selective N-Methyl-D-Aspartate Receptor Modulators
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Chapter 1. Total synthesis of Fumonisin B1 Chapter 2.
Synthesis of Unnatural Sphingolipids: 1-deoxy-5-hydroxysphinganine
and its diastereomers Chapter 3. Development of Methodology:
Synthesis of cis- and trans-homoallylic alcohols
Chapter 4. Human Milk Oligosaccharides: Synthesis of Natural and
Unnatural oligomers
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I. A New Approach to the Synthesis of a Key 5-Oxo-Pyridinyl
Molybdenum Scaffold. II. Oxidative Demetalation of
η3-Allylmolybdenum Complexes with an Oxygen
Nucleophile; Application to the Synthesis of (+)-Isofebrifugine
Analogs
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The Catalytic Aerobic Oxidation of Aldehyde and Alcohol Substrates with Redox-Active Ligand-Supported Earth-Abundant Metal Catalysts
25 of 100
Synthesis, characterization, and biological stabilities of
gold(III) di-2-pyridyl and sec-butyl-phenanthroline
complexes
26 of 100
The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
27 of 100
Concise Total Synthesis of (-)-D-erythro-Sphingosine and Sphingosine-1-Phosphate
28 of 100
Copper-Catalyzed C-N Bond Formation from Ketoxime O-Carboxylates and Application to Pyridine Synthesis
29 of 100
Desulfitative Coupling Reactions for the Mild Construction of Carbon-Carbon, Carbon-Nitrogen, and Carbon-Oxygen Bonds
30 of 100
Towards the Synthesis of Marine Polyether Triterpenes
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Acylative Redox Dehydration of Carboxylic Acids and Benzoisothiazolones in the Synthesis of Thioesters with Triethylphosphite as a Terminal Reductant
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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Investigating Sustainable Precious Metal Catalysis: Routine Dirhodium Catalyzed Carbene Reactions with High Yield and Enantioselectivity at Low Loadings
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
35 of 100
Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of
Novel Therapeutic Agents for Cocaine Abuse
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Synthesis and Characterization of
N-alkyl-3-(2,4-dichlorophenyl)-N-fluoroalkyl-2,5-
dimethylpyrazolo[1,5-a]pyrimidin-7-amines as Potential CRF1
Receptor PET Radiotracers
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A Methodological Study of Enantioselective Dirhodium(II)-Catalyzed Cyclopropanations at Low Catalyst Loadings
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Incorporating the Scientific Contributions of Research Faculty into
the Chemical Education of Undergraduate Students at Emory
University
39 of 100
Modular Synthesis of Polyketide Natural Products: Synthesis of
the C9-C27 Degradation Product of Aflastatin A and Total Synthesis
of Fostriecin
40 of 100
TARGETING MIXED LINEAGE LEUKEMIA AS ANTICANCER THERAPY FOR
INFANTILE ACUTE LYMPHOBLASTIC LEUKEMIA THROUGH THE SYNTHESIS OF
NOVEL COMPOUNDS
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Development of a Copper Catalyzed Aminoacetoxylation Reaction of
Olefins, Development of an Intermolecular and Diastereoselective
Iminium Cascade Reaction and Studies Towards the Synthesis of a
Malagasy Alkaloid
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Modular Synthesis of Asymmetric Triazacyclononane Derivatives and Potential Aerobic Copper Oxidation Catalyst Supported by a Bridging Bulky Triazacyclononane
43 of 100
Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of
Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of
Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition
of HIV Reverse Transcriptase
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Stereocontrolled Synthesis of Ketones bearing Stereogenic Centers
by Desulfitative Cross-Coupling of Thiol Esters and Organostannanes
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Chapter 1: The development of a model system for the B-ring of
brevenal and methods for the formation of seven-membered rings.
Chapter 2: Iterative alkyne-epoxide cross-couplings toward the
total synthesis of PM toxin A. Chapter 3: The development of
synthons for 1,3-dimethylallylation of aldehydes.
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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
48 of 100
In Situ Kinetic Studies of Reactions Involving Dirhodium(II)
Donor/Acceptor Carbenes
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Investigation of C-H Bond Oxidation Reactions: I. Asymmetric
Amination of C-H Bonds Using Ruthenium(II) Catalysts II.
Investigation of Structural Determinants of Monoamine Oxidase B
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Part I: Synthesis of Cyclobutyl Nucleoside and NucleotideAnalogues as HIV-1 Reverse Transcriptase InhibitorsPart II: Improvement of Glycosylation Regioselectivity in PurineNucleoside Analogue SynthesisPart III: Enantioselective Synthesis ofβ-D-Dioxolane-T andβ-D-FDOC
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Organometallic Scaffolding as a Practical Approach toDiversity-Oriented Synthesis: Stereo- and RegiocontrolledSequential Functionalization of Pyranylalkylidene AllylmolybdenumComplexes
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Utilization of a Michael Addition-Dipolar Cycloaddition Cascade Involving 2,3- bis(Phenylsulfonyl)butadiene for Alkaloid Synthesis
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Developing Chiral Synthons for Polyketide-Based Natural Product Synthesis via Stereospecific Oxonia-Cope Rearrangement
54 of 100
Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions
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Explorations of Metallocarbene and Metallonitrene Reactive
Intermediate Chemistry for the Development of Synthetically Useful
New Reactions
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Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin
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Progress Toward the Total Synthesis of PM-toxin A And Future
Development of Mild Lewis Acid Activated Alkynylation of Epoxides
58 of 100
A Thorough Investigation of the Characteristic Phosphorus Couplings
and 31P NMR Analysis in Attempts to Synthesize an Ifosfamide Analog
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I. Addressing the Regioselectivity Problem in Organic Synthesis.II. A-B-A-B-A Block Amphiphiles. Balance between Hydrophilic andHydrophobic Segmentation.
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Chapter 1. Part 1: Novel Synthesis and Biological Evaluation of1,5-Linked D-Mannoseptanosides. Part 2: Synthesis ofD-Glucoseptanosides Chapter 2. Biomimetic Total Synthesis of theProposed Structure of ent-Muzitone
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Rhodium(II)-Catalyzed Asymmetric Transformations and Their
Applications in The Development of Novel CNS Drug Candidates
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Synthesis and Characterization of Organic and Inorganic
Compounds with Biological and Material Applications
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Synthesis of Highly Functionalized Pyrroles Using a Dirhodium
Catalyst
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SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID
REACTIONS
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Part I: Design, Synthesis, and Biological Activity of NMDA
Receptor Antagonists
Part II: Design and Synthesis of Measles Virus Inhibitors
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Chapter 1. Biomimetic Total Synthesis of ent-Durgamone, ent-Nakorone and ent-Abudinol B Chapter 2. Biomimetic Synthesis of Fused Polypyrans
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Aerobic, Medal Mediated Ketone Synthesis from Thiol Esters and Boronic Acids
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Part I: Conformational Analysis of Bioactive Molecules inSolutionPart II: Structure-Based Design of Selective Inhibitors ofCyclin-Dependent Kinase 7
69 of 100
Rhodium Alkenylcarbenes: Novel Reactivity and Precursors
70 of 100
Ambient Temperature Synthesis of High Enantiopurity N-ProtectedPeptidyl Ketone by Desulfitative Cross Coupling of Peptidyl ThiolEsters and Boronic Acids
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Exploring Catalytic Properties of Polyoxometalates in Aerobic
Decontamination and Water Oxidation
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Practical Enhancement and Applications of Dirhodium Catalyzed Reactions of Donor/Acceptor Carbenes
73 of 100
Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Antagonists
74 of 100
Synthesis of Ellagic Acid Glycoside Derivatives found in Rubus
ulmifolius
75 of 100
Progress Toward a Common Intermediate for C1 Modified
Enigmols
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Synthesis and Reactivity of Benzo[1,3,2]dithiazole 1,1-dioxides: Implications in Acylative Redox Dehydration
77 of 100
The Polyoxometalate / NOx / Brx Catalystsfor Aerobic Sulfoxidations
78 of 100
Mild Amide and Peptide Constructions by the Condensation of
O-Silylthionoesters with Amines and Metal Mediated Cross-Coupling
Reactions for Carbon-Carbon Bond Formation
79 of 100
Computational Studies of Ligand Protein Interactions Part I: TheT-Taxol Conformation Part II: Elucidating Interdependent BindingSites on Tubulin
80 of 100
Synthesis of Those Sectors of Saccharomicin A and B ContainingSaccharosamine and the Discovery of a Novel 4-H-1,3-OxazineSynthesis
81 of 100
Part 1: Stereoselective Synthesis of Quaternary Center BearingAzetines and β-Amino Acid Derivatives. Part 2: Natural andEnantiomeric Progesterone Analogues for the Treatment of TraumaticBrain Injury
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ASYMMETRIC REACTIONS OF DONOR/ACCEPTOR RHODIUM CARBENOIDS: FROM
FORMAL CYCLOADDITIONS TO C-H INSERTION
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Organometallic Enantiomeric Scaffolds in the Synthesis of
Alkaloids: I. Homo-SN2´-like Reaction/Annulative Demetallation
and the Application in the Synthesis of (+)-Isofebrifugine II.
Uncatalyzed Electrophilic C-C Bond Forming Reactions of Pyranyl and
Pyridinyl Molybdenum Complexes
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Design, Synthesis, and Biologic Evaluation of
Tetrahydroisoquinoline-Based CXCR4 Modulators
85 of 100
Chiral dirhodium catalysts design, synthesis and application in
asymmetric carbenoid transformations and silver-catalysis of
vinylogous fluorination
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Synthesis and Characterization of Unusal Amphiphiles Part I. Nonsteroidal Facial Amphiphiles Part II. Diketopiperazine Derived Surfactants
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Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Modulators
88 of 100
RHODIUM CATALYZED ASYMMETRIC TRANSFORMATIONS OF VINYLCARBENOIDS
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Application of IMDAF and Rh(II)-Catalyzed Cascade Reactions forTotal Synthesis of Natural Products
90 of 100
Development of a Novel Cascade Cyclization Reaction and its
Application Towards the Total Synthesis of Malagashanine: A
Chloroquine Efflux Inhibitor
91 of 100
Design and Development of Novel Methods for C-H Functionalization
for Amination and C-C Bond Formation
92 of 100
[5+2] Cycloadditions to Form Oxobicyclo[3.2.1]octanes
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CYCLOADDITIONS AND YLIDE CHEMISTRY OF DONOR/ACCEPTOR- SUBSTITUTED
CARBENES FROM THERMAL DECOMPOSITION OF ARYLDIAZOCARBONYL COMPOUNDS
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Studies toward the total synthesis of altromycin natural products
95 of 100
Ring Chain Isomerism: Ligands for Mediating Two-Electron
Reactivity with First-Row Transition Metals
96 of 100
Synthesis and Characterization of Organic and Inorganic
Compounds with Biological Applications
97 of 100
Development of a Redox-Active Ligand Framework: A Novel Approach towards Reactivity in C−H Functionalization Reactions
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Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis,
and Biological Evaluation of a Novel Class of Allosteric Modulators
of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of
Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and
Conformational Analysis of Structurally Similar CXCR4 Antagonists
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Design, Synthesis and Biological Evaluation of C4-C9 Bridged
Epothilone Analogs
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