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Directed Evolution and Computational Design of Nucleoside Analog
Kinases
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Synthesis of protein-based polymers with the potential to form
physically and covalently cross-linked networks
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Amyloid Conformational Diversity Accessed By Truncations of a
Native Protein Fold
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Enzyme Engineering
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Nanoscale Tools to Expand the Biophysical Understanding of
Epidermal Growth Factor Receptor Function
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Programmed Self-assembly of Coiled-coil Peptides
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Investigation of C-H Bond Oxidation Reactions: I. Asymmetric
Amination of C-H Bonds Using Ruthenium(II) Catalysts II.
Investigation of Structural Determinants of Monoamine Oxidase B
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Development of Monocarbonyl Curcumin Analogues Towards Treating
Tuberculosis and Cancer
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Muti-site specific incorporation of non-canonical amino acids for
biomaterials design
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Generating designer enzymes for therapeutic and industrial
applications
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THE BROAD-HOST-RANGE PATHOGENESIS OF AGROBACTERIUM
TUMEFACIENS: SUCCESSFUL COUPLING THE MOTIONS AND DOMAIN
INTERACTIONS WITHIN VIRA TO INTEGRATE SIGNAL SENSING
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Amyloid: Merging the Properties of Membranes and Enzymes
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Engineering Asymmetric Peptide Membranes
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Conformational Exchange: A Common Mechanism for Amyloid Assembly
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I: Expanding Genetic Code in S. cevevisiae with an
Orthogonal tRNATrp/UCA/ Tryptophanyl tRNA Synthetase
Pair II: Synthetic Yeast Prions based on a Non-NQ-rich
Amyloidogenic Sequence Derived from the NAC Protein Sequence of
α-Synuclein.
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
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Development and Application of Synthetic Riboswitches as Tools
to Study Bacterial Pathogenesis
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Engineering The Substrate Specificity Of Human Deoxycytidine Kinase
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Engineering Candida antarctica lipase B by circular permutation and incremental truncation
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Encapsulation of Small Molecules in Peptide Nanotubes
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