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The Design, Synthesis, and Biological Evaluation of Novel Prodrugs and Antiviral Agents for HIV and Other Chronic Viral Infections
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Site-selective and Stereoselective Functionalization of Non-Activated C–H Bond
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Structure-Activity Relationship and Quantitative Structure-Activity Relationship of GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor
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Natural and Synthetic Compounds as Tools to Overcome Antibiotic Resistance
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Synthesis of small molecule therapeutics and ligands utilizing rhodium carbenoid chemistry
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Chemical Approaches to Elucidate Novel Facets of Nucleic Acid Metabolism and Signaling
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Promysalin and CD437: Compounds Investigating New Antibacterial Mechanisms
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The Design, Synthesis, and Biological Evaluation of Subunit-Selective Modulators of the N-Methyl-D-Aspartate Receptor
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Synthesis of bulky 1,4,7-triazacylcononanes, including asymmetric derivatives; Esterification by aryl-diselenide catalyzed redox condensation; 1-amino-3,4-difluorocyclopentane-1-carboxylic acids as PET imaging agents
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The Development of Complementary Allylic C-H Amination and Amidation Conditions for the Regioselective Functionalization of Group IX MCp*-π-Allyl Intermediates
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The Synthesis and Application of a Series of C4-Symmetric Dirhodium Catalysts Derived from 1-(2-Chlorophenyl)-2,2-Diphenylcyclopropanecarboxylate Ligands
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Complementary Approaches to Combat Antibacterial Resistance: Metal-binding Small Molecules and Quaternary Ammonium Compounds
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Structure, Synthesis, and Reactivity: Intentional Design Approaches to Agonists for Liver Receptor Homolog-1 and Photochemical Arene Dearomatization
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Carolacton and Honokiol: using natural product inspiration to target the oral microbiome
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Synthesis, Structure-Activity Relationship, and Biological Evaluation of Subunit-Selective NMDA Receptor Modulators
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Reductive Processes Enabled by Photoredox for the Synthesis and Modification of Pharmaceutically Relevant Molecules
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Development of Intermolecular Couplings of Aryl Radical Species with Olefins
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Radical Conjugate Addition of N-Heterocycles and Tertiary Amines
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Development and Applications of a New Dirhodium(II) Tetracarboxylate Catalyst and Asymmetric Cyclopropanation of Heterocyclic Compounds
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Exploring the Influence of Dirhodium Catalyst Structure on the Regio- and Stereoselectivity Properties of Donor/Acceptor Carbenes
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Allylic C-H Arylation, Enantioselective Catalyst Development, and Enantioselective Allylic C-H Amidation
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Broadening the applications of rhodium donor/acceptor carbene mediated C–H functionalization
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Harnessing the Dual Nature of Peptide Nucleic Acids
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Studies Towards the Synthesis of Malagasy Alkaloids, and Development and Applications of Regio- and Enantioselective Group IX Metal-Catalysed Reactions
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The Development and Mechanistic Studies of Group(IX)Cp*-Catalyzed Allylic C–H Functionalization Reactions Proceeding via a π-allyl Intermediate
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Design and Synthesis of New Liver Receptor Homolog-1 Modulators and Probes
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Probing Bacterial Mechanisms via Small Molecule Antibiotics
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GluN2C/D subunit selective antagonist for NMDARs: 997 Series
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Developing First-Row Transition Metal Complexes for Green Catalytic C–H Activation and Oxidations
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Intercepting Photochemically Generated Aminoalkyl and Aryl Radical Intermediates to Access Complexity Quickly
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The Iterative Design of Aptamer-Functionalized Membranes to Enable Detection, Sequestration, and Recovery of Small-Molecule Compounds
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Design and Synthesis of a PD-L1 Radioligand for Diagnostic Imaging and Development and Optimization of a Potent Liver Receptor Homolog-1 Agonist
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Arene Dearomatization via Radical Hydrofunctionalization
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EXPANDING THE SCOPE AND APPLICATION OF N-SULFONYL-1,2,3-TRIAZOLES AS ALTERNATE PRECURSORS TO DONOR/ACCEPTOR RHODIUM CARBENES
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Design, Synthesis, and Utility of Group IX Metal Catalysts for C–H Functionalization
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Targeting Bacterial Tolerance and Resistance with Small Molecules
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Practical Application and In Situ Kinetic Studies of Dirhodium(II) Tetracarboxylate Catalyzed Carbene Reactions
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Leveraging Organic Synthesis to Disrupt and Understand Essential Bacterial Processes
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C-H Functionalization Inspired Total Synthesis and New Donor/Acceptor Carbenes for Asymmetric C-H Functionalization
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Total synthesis and biological investigations of natural product inspired antimicrobials
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Asymmetric Rhodium(II)-Carbene C-H Functionalization: A Complementary Tool To Synthetic Disconnection Strategies
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Leveraging Chemical Tools to Target Bacterial Membranes and Combat Antimicrobial Resistance
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Synthesis and Biological Investigation of Membrane-targeting Antimicrobials
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A Three-Pronged Approach to Combatting Antibiotic Resistance
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Development of Chemical Methods for Labeling Monomethyl Lysine Post-Translational Modification and Serine and their Applications.
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Exploration of Bilingual Peptide Nucleic Acids
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Membranes & Metals: Bacterial Targets to Fight Antibiotic Resistance
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Studies in Small Molecule Drug Discovery: Part I. Synthesis of Novel Nucleoside-Based Antivirals to Treat Hepatitis C; Part II. Validation and Implementation of a Machine Learning Algorithm to Create a Safer Kinase Inhibitor as a Potential First-in-Class Antiparkinsonian Agent
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Developing Chemical Tools for Selective Peptide Modification
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Chemo and Site Selective Modification of Proteins and Chemical Tools for Studying Mono-Methyl Lysine (Kme)
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Design and Synthesis of Chemical Modulators for Altered Activity of Nuclear Receptor Liver Receptor Homolog-1 and Synthesis of Spirocyclic Piperidines via Radical Hydroarylation
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Radical Reactivity via Transient Carbon Dioxide Radical Anion (CO2•−)
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Overcoming the Limitations of Rhodium-Catalyzed Asymmetric Cyclopropanation and Other Adventures in Strained Ring Synthesis
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Overcoming Antibacterial Resistance through Synthesis of Small Molecules Targeting Efflux Mechanisms
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Natural Product Inspired Complementary Approaches to Counter Antimicrobial Resistance: Synthetic and Biological Investigations of Antibacterial Small Molecules
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Group IX Metal-Catalyzed C–H Activation Towards the Development of New Synthetic Strategies
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The Development of Planar Chiral Indenyl Catalysts and the Progress Towards Synthesis of the Western Macrocycle of Darobactin A
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Metal Catalyst Methodology Development towards Carbon-Oxygen Bond Formation: Synthesis of Vinyl Ethers and Vinyl Esters
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DNA mechanocapsules: Force responsive tetrahedral DNA nanostructures with modular cargo delivery for targeting mechanical phenotypes of diseases
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Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
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Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
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Developing Transition Metal Catalysts that Incorporate Redox-Active Ligand Frameworks for Sustainable Catalysis
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