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Modification of Native Biomolecular Functions to Identify and Control Adenosine-to-Inosine Editing of RNA Substrates
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Protein and Solvent Dynamical Contributions to Reactions of the 2-Aminopropanol Substrate Radical in Ethanolamine Ammonia-Lyase
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Platelet Clearance and Mechanosensation via GPIb-IX-V: How Platelets Use the Force
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COMPARING AND CONTRASTING TWO PLANT PATHOGENS PROVIDE A UNIQUE
WINDOW INTO THE DIFFERENCES IN THE INNATE IMMUNE RESPONSES BETWEEN
DICOTS AND MONOCOTS
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MUTUALISM IN NUCLEIC ACID/PEPTIDE DOMAIN ARRAYS: IMPLICATIONS FOR
ORIGINS OF LIFE, NANOTECHNOLOGY, AND DISEASE
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
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I: Expanding Genetic Code in S. cevevisiae with an
Orthogonal tRNATrp/UCA/ Tryptophanyl tRNA Synthetase
Pair II: Synthetic Yeast Prions based on a Non-NQ-rich
Amyloidogenic Sequence Derived from the NAC Protein Sequence of
α-Synuclein.
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Protein-based Tension Probes: From Mapping Integrin Adhesion
Forces to the Mechanopharmacology of Smooth Muscle Cells
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EXTENDING THE CENTRAL DOGMA: DEVELOPING NOVEL INFORMATIONAL
BIOPOLYMERS
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Fundamental properties and applications of surface confined enzymes in gene regulation and molecular motors
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Conformational Exchange: A Common Mechanism for Amyloid Assembly
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Engineering Asymmetric Peptide Membranes
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Towards the Development of Non-Toxic Therapeutics in the Fight
Against Cancer
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An Approach to Generate Ultra-Robust and Highly Modular Molecular
Tension Probes and Thermo-Responsive Enzymatic Nanoreactors to
Regulate Reaction Rate
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From Amyloid to Copper Arrays: The design of a functional
Metalloamyloid Nanostructure (MAN)
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Heterogeneity in fast-folding beta proteins
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Amyloid: Merging the Properties of Membranes and Enzymes
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Studies on the Activation Mechanism and Identification of aSubstrate for Giant Kinases in C. elegans Muscle
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Encapsulation of Small Molecules in Peptide Nanotubes
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THE BROAD-HOST-RANGE PATHOGENESIS OF AGROBACTERIUM
TUMEFACIENS: SUCCESSFUL COUPLING THE MOTIONS AND DOMAIN
INTERACTIONS WITHIN VIRA TO INTEGRATE SIGNAL SENSING
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Generating designer enzymes for therapeutic and industrial
applications
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Expression and Functional Characterization of Monoamine Oxidasefrom the Zebrafish (Danio Rerio): Comparisons with HumanMonoamine Oxidases A and B
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Metabolism of CD4+ Th1 and Th2 cells
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Multidisciplinary Assessments of the Structure and Function ofCo-enzyme B12-Dependent Enzyme EthanolamineAmmonia-lyase
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Advanced Time-Resolved Fluorescence Microscopy Techniques for the
Investigation of Peptide Self-Assembly
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Analytical Methods for Pesticides in Food and ResidentialDust
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Development of Fluorescence-based Molecular Tension Probes to Investigate Cellular Mechanical Forces
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Design, Synthesis, and Biologic Evaluation of
Tetrahydroisoquinoline-Based CXCR4 Modulators
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Biosynthesis and Characterization of Biodegradable Materials Based on Elastin Mimetic Polypeptide
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Self-assembly of porousa-helical nanosheets
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Understanding Synthetic Riboswitch Mechanism and Creating Predictive Biophysical Model for Designing Novel Synthetic Riboswitches
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Re-Inventing Template-Directed Replication in Dynamic Chemical Networks
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Conformational evolution in amyloid self-assembly
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The Design of Theophylline Sensing Riboswitches in Agrobacteriumtumefaciens and Their Application in Reprogramming theVirA/VirG Two-Component System
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From Aptamer to Riboswitch: High-throughput Screens and Selections
for the Identification and Creation of Synthetic Riboswitches
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Generation of Novel Yeast Prions through Domain Substitutions of Saccharomyces cerevisiae Sup35p
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Biological Engineering with Chemical-Sensing MacromolecularSwitches: I. Discovery and Applications of Small-Molecule DependentSynthetic Riboswitches II. A Genetic Toolbox for CreatingReversible Ca 2+ -Sensitive Biomaterials
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Nanoscale Tools to Expand the Biophysical Understanding of
Epidermal Growth Factor Receptor Function
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Enzyme Engineering
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Engineering Control of Gene Expression in Bacteria Using RNA-Small Molecule Interactions
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Modulating Amyloid Peptide Self-Assembly With Nucleobase Incorporation
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Regulation and Characterization of Amyloid Architectures: Insight
into Amyloid Cytotoxicity and Molecular Self-Assembly
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Exploring the peptide nanotube formation from the self-assembly of the Aβ(13-21)K16A peptide in the presence of Zinc ions
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Creation of Tubular α− Helical Assemblies Through
Seven-Helix Coiled Coils
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Energetic Contribution of Amyloid Self-assembly
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Semagenesis & Xenognosis: Translating the Molecular Dialogues of Host-Parasite Interactions
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Photolabeling of the Human Dopamine Transporter and theReactivity of Aryl Azides with Amino Acid Analogs
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Degradation of pesticides in food and beverages: Implications for
risk assessment
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Amyloid Conformational Diversity Accessed By Truncations of a
Native Protein Fold
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A Type-II Thymidine Kinase from Thermotoga maritima: KineticCharacterization, Substrate Binding, and Oligomerization
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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Signal Perception and Transmission through the VirA/VirG Two-Component System in Agrobacterium Tumefaciens
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Biomaterials Design: Creation of a novel orthogonal translationalsystem in E. coli for the site-specific incorporation ofproline analogues in biosynthetic protein materials
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14N electron spin echo envelope modulation
Spectroscopy of Cu(II)-imidazole coordination structure in the
amyloid-
beta protein of Alzheimer's disease and in model
Amyloid-beta peptides and complexes
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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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Directed Evolution and Computational Design of Nucleoside Analog
Kinases
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The Etp1 Ubiquitin Ligase Regulates Ubiquitin Homeostasis in Yeast
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Metastable Phases Direct Polymer Emergence and Evolution in Dynamic Chemical Networks
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Cross-ß Folds of Amyloid as a Versatile Self-Propagating Catalyst
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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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Amplification of amyloid-beta strains and their connection to tau in Alzheimer’s Disease
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