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Directed Evolution and Computational Design of Nucleoside Analog
Kinases
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Amyloid Conformational Diversity Accessed By Truncations of a
Native Protein Fold
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Enzyme Engineering
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Nanoscale Tools to Expand the Biophysical Understanding of
Epidermal Growth Factor Receptor Function
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Generating designer enzymes for therapeutic and industrial
applications
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THE BROAD-HOST-RANGE PATHOGENESIS OF AGROBACTERIUM
TUMEFACIENS: SUCCESSFUL COUPLING THE MOTIONS AND DOMAIN
INTERACTIONS WITHIN VIRA TO INTEGRATE SIGNAL SENSING
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Amyloid: Merging the Properties of Membranes and Enzymes
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Engineering Asymmetric Peptide Membranes
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Conformational Exchange: A Common Mechanism for Amyloid Assembly
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I: Expanding Genetic Code in S. cevevisiae with an
Orthogonal tRNATrp/UCA/ Tryptophanyl tRNA Synthetase
Pair II: Synthetic Yeast Prions based on a Non-NQ-rich
Amyloidogenic Sequence Derived from the NAC Protein Sequence of
α-Synuclein.
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
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Encapsulation of Small Molecules in Peptide Nanotubes
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Expression and Functional Characterization of Monoamine Oxidasefrom the Zebrafish (Danio Rerio): Comparisons with HumanMonoamine Oxidases A and B
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The Design of Theophylline Sensing Riboswitches in Agrobacteriumtumefaciens and Their Application in Reprogramming theVirA/VirG Two-Component System
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Generation of Novel Yeast Prions through Domain Substitutions of Saccharomyces cerevisiae Sup35p
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Biological Engineering with Chemical-Sensing MacromolecularSwitches: I. Discovery and Applications of Small-Molecule DependentSynthetic Riboswitches II. A Genetic Toolbox for CreatingReversible Ca 2+ -Sensitive Biomaterials
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Exploring the peptide nanotube formation from the self-assembly of the Aβ(13-21)K16A peptide in the presence of Zinc ions
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Energetic Contribution of Amyloid Self-assembly
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Semagenesis & Xenognosis: Translating the Molecular Dialogues of Host-Parasite Interactions
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Photolabeling of the Human Dopamine Transporter and theReactivity of Aryl Azides with Amino Acid Analogs
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A Type-II Thymidine Kinase from Thermotoga maritima: KineticCharacterization, Substrate Binding, and Oligomerization
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Biomaterials Design: Creation of a novel orthogonal translationalsystem in E. coli for the site-specific incorporation ofproline analogues in biosynthetic protein materials
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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Cross-ß Folds of Amyloid as a Versatile Self-Propagating Catalyst
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Heterogeneity in fast-folding beta proteins
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Development of Fluorescence-based Molecular Tension Probes to Investigate Cellular Mechanical Forces
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Understanding Synthetic Riboswitch Mechanism and Creating Predictive Biophysical Model for Designing Novel Synthetic Riboswitches
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Metastable Phases Direct Polymer Emergence and Evolution in Dynamic Chemical Networks
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Amplification of amyloid-beta strains and their connection to tau in Alzheimer’s Disease
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