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Lynn, David, Emory University
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Committee
Conticello, Vincent, Emory University
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Research Field
Chemistry, Biochemistry
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School
Laney Graduate School
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Submission Type
Dissertation
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Enzyme Engineering
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Conformational Exchange: A Common Mechanism for Amyloid Assembly
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I: Expanding Genetic Code in S. cevevisiae with an
Orthogonal tRNATrp/UCA/ Tryptophanyl tRNA Synthetase
Pair II: Synthetic Yeast Prions based on a Non-NQ-rich
Amyloidogenic Sequence Derived from the NAC Protein Sequence of
α-Synuclein.
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Biosynthesis and Characterization of Biodegradable Materials Based on Elastin Mimetic Polypeptide
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Generation of Novel Yeast Prions through Domain Substitutions of Saccharomyces cerevisiae Sup35p
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Biological Engineering with Chemical-Sensing MacromolecularSwitches: I. Discovery and Applications of Small-Molecule DependentSynthetic Riboswitches II. A Genetic Toolbox for CreatingReversible Ca 2+ -Sensitive Biomaterials
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Exploring the peptide nanotube formation from the self-assembly of the Aβ(13-21)K16A peptide in the presence of Zinc ions
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Semagenesis & Xenognosis: Translating the Molecular Dialogues of Host-Parasite Interactions
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Biomaterials Design: Creation of a novel orthogonal translationalsystem in E. coli for the site-specific incorporation ofproline analogues in biosynthetic protein materials
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Cross-ß Folds of Amyloid as a Versatile Self-Propagating Catalyst
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Understanding Synthetic Riboswitch Mechanism and Creating Predictive Biophysical Model for Designing Novel Synthetic Riboswitches
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Metastable Phases Direct Polymer Emergence and Evolution in Dynamic Chemical Networks
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Amplification of amyloid-beta strains and their connection to tau in Alzheimer’s Disease
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