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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
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Chapter 1: The development of a model system for the B-ring of
brevenal and methods for the formation of seven-membered rings.
Chapter 2: Iterative alkyne-epoxide cross-couplings toward the
total synthesis of PM toxin A. Chapter 3: The development of
synthons for 1,3-dimethylallylation of aldehydes.
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of
Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of
Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition
of HIV Reverse Transcriptase
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Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Development of a Copper Catalyzed Aminoacetoxylation Reaction of
Olefins, Development of an Intermolecular and Diastereoselective
Iminium Cascade Reaction and Studies Towards the Synthesis of a
Malagasy Alkaloid
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Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of
Novel Therapeutic Agents for Cocaine Abuse
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Identification of Small Molecule Inhibitors of I-κB
Kinase
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Analysis of the EF24-modulated signaling pathways for thedevelopment of novel cancer combination therapies
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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Acylative Redox Dehydration of Carboxylic Acids and Benzoisothiazolones in the Synthesis of Thioesters with Triethylphosphite as a Terminal Reductant
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Towards the Synthesis of Marine Polyether Triterpenes
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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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I. A New Approach to the Synthesis of a Key 5-Oxo-Pyridinyl
Molybdenum Scaffold. II. Oxidative Demetalation of
η3-Allylmolybdenum Complexes with an Oxygen
Nucleophile; Application to the Synthesis of (+)-Isofebrifugine
Analogs
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Investigation and Modeling of Binding Modes of Novel Small-Molecule
Nox2 Inhibitors
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Chapter 1. Total synthesis of Fumonisin B1 Chapter 2.
Synthesis of Unnatural Sphingolipids: 1-deoxy-5-hydroxysphinganine
and its diastereomers Chapter 3. Development of Methodology:
Synthesis of cis- and trans-homoallylic alcohols
Chapter 4. Human Milk Oligosaccharides: Synthesis of Natural and
Unnatural oligomers
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Design, Synthesis, and Biological Evaluation of Subunit
Selective N-Methyl-D-Aspartate Receptor Modulators
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Part 1: Synthesis and Anti-HIV Activity of Novel CyclobutylNucleoside and Nucleotide Analogs, Part 2: Synthesis of FluorescentNucleoside Analogs, Part 3: Synthesis of Abacavir
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