Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the Treatment of Hepatitis C Virus

Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis, and Biological Evaluation of a Novel Class of Allosteric Modulators of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and Conformational Analysis of Structurally Similar CXCR4 Antagonists

Generating designer enzymes for therapeutic and industrial applications

Structural Determinants of Activity, Mechanism and Structure Activity Relationships of Novel GluN2C/D Subunit Selective Antagonists of the N-methyl-D-Aspartate Receptor

Development of Monocarbonyl Curcumin Analogues Towards Treating Tuberculosis and Cancer

Chapter 1: The development of a model system for the B-ring of brevenal and methods for the formation of seven-membered rings. Chapter 2: Iterative alkyne-epoxide cross-couplings toward the total synthesis of PM toxin A. Chapter 3: The development of synthons for 1,3-dimethylallylation of aldehydes.

Paclitaxel and Cyclostreptin in theTubulin Binding Site

Design, Synthesis, and Biological Evaluation of Subunit Selective N-Methyl-D-Aspartate Receptor Modulators