Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the Treatment of Hepatitis C Virus

Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis, and Biological Evaluation of a Novel Class of Allosteric Modulators of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and Conformational Analysis of Structurally Similar CXCR4 Antagonists

Chapter 1: The development of a model system for the B-ring of brevenal and methods for the formation of seven-membered rings. Chapter 2: Iterative alkyne-epoxide cross-couplings toward the total synthesis of PM toxin A. Chapter 3: The development of synthons for 1,3-dimethylallylation of aldehydes.

Design, Synthesis, and Biological Evaluation of Subunit Selective N-Methyl-D-Aspartate Receptor Modulators