Multi-mechanism antiretroviral approach targeting macrophage derived viral sanctuaries

SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM CARBENOID CHEMISTRY

Part I. Design of a novel class of reversible non-covalent small molecule inhibitors for human Granzyme B (hGrB) Part II. Curcumin and mimics as proteasome inhibitors Part III. Design of novel coactivator binding inhibitors (CBIs) for the estrogen receptor α : break the 1µM barrier

Development of a novel stereo-selective synthetic route towards Pumiliotoxin C, potent neurotoxin, via asymmetric Diels-Alder and sequential protonation-nucleophilic addition as key reaction steps

SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID REACTIONS

Screening, hit expansion and mechanistic studies for natural product analogs derived from traditional herbal medicine: curcumin and triptolide.

Use of Receptor-Based Drug Design and Applications in the Study of finding antagonists for MD-2/TLR4, GLP and CXCR4

Design, Synthesis, and Biological Evaluation of Subunit Selective N-Methyl-D-Aspartate Receptor Modulators