Towards the Development of Non-Toxic Therapeutics in the Fight Against Cancer

Use of Furans as Vehicles for Heterocyclic Synthesis: Anaza-Achmatowicz Approach to Piperidine Alkaloids, a Novel OxidativeRoute to Acyloxypyrrolinones, and IMDAF Studies Toward a Synthesisof Minfiensine and Morphine

Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone AnalogsPart II: Discovery of Small Molecule CXCR4 Antagonists

Design, Synthesis and Biological Evaluation of C4-C9 Bridged Epothilone Analogs

Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis, and Biological Evaluation of a Novel Class of Allosteric Modulators of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and Conformational Analysis of Structurally Similar CXCR4 Antagonists

Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Modulators

Synthesis and Characterization of Unusal Amphiphiles Part I. Nonsteroidal Facial Amphiphiles Part II. Diketopiperazine Derived Surfactants

Design, Synthesis, and Biologic Evaluation of Tetrahydroisoquinoline-Based CXCR4 Modulators

Organometallic Enantiomeric Scaffolds in the Synthesis of Alkaloids: I. Homo-SN2´-like Reaction/Annulative Demetallation and the Application in the Synthesis of (+)-Isofebrifugine II. Uncatalyzed Electrophilic C-C Bond Forming Reactions of Pyranyl and Pyridinyl Molybdenum Complexes

ASYMMETRIC REACTIONS OF DONOR/ACCEPTOR RHODIUM CARBENOIDS: FROM FORMAL CYCLOADDITIONS TO C-H INSERTION

Part 1: Stereoselective Synthesis of Quaternary Center BearingAzetines and β-Amino Acid Derivatives. Part 2: Natural andEnantiomeric Progesterone Analogues for the Treatment of TraumaticBrain Injury

Synthesis of Those Sectors of Saccharomicin A and B ContainingSaccharosamine and the Discovery of a Novel 4-H-1,3-OxazineSynthesis

Computational Studies of Ligand Protein Interactions Part I: TheT-Taxol Conformation Part II: Elucidating Interdependent BindingSites on Tubulin

Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Antagonists

Rhodium Alkenylcarbenes: Novel Reactivity and Precursors

Part I: Conformational Analysis of Bioactive Molecules inSolutionPart II: Structure-Based Design of Selective Inhibitors ofCyclin-Dependent Kinase 7

SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID REACTIONS

Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin

Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions