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Validation of Receptor-Based Drug Design and Applications in the
Study of IKKs, Truncated Taxane and LRH-1
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Rhodium Alkenylcarbenes: Novel Reactivity and Precursors
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Part I: Conformational Analysis of Bioactive Molecules inSolutionPart II: Structure-Based Design of Selective Inhibitors ofCyclin-Dependent Kinase 7
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Development of Monocarbonyl Curcumin Analogues Towards Treating
Tuberculosis and Cancer
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SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID
REACTIONS
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Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin
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Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions
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Use of Receptor-Based Drug Design and Applications in the Study
of finding antagonists for MD-2/TLR4, GLP and CXCR4
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Part I: Synthesis of Cyclobutyl Nucleoside and NucleotideAnalogues as HIV-1 Reverse Transcriptase InhibitorsPart II: Improvement of Glycosylation Regioselectivity in PurineNucleoside Analogue SynthesisPart III: Enantioselective Synthesis ofβ-D-Dioxolane-T andβ-D-FDOC
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Investigation of C-H Bond Oxidation Reactions: I. Asymmetric
Amination of C-H Bonds Using Ruthenium(II) Catalysts II.
Investigation of Structural Determinants of Monoamine Oxidase B
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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
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Chapter 1: The development of a model system for the B-ring of
brevenal and methods for the formation of seven-membered rings.
Chapter 2: Iterative alkyne-epoxide cross-couplings toward the
total synthesis of PM toxin A. Chapter 3: The development of
synthons for 1,3-dimethylallylation of aldehydes.
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of
Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of
Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition
of HIV Reverse Transcriptase
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Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Development of a Copper Catalyzed Aminoacetoxylation Reaction of
Olefins, Development of an Intermolecular and Diastereoselective
Iminium Cascade Reaction and Studies Towards the Synthesis of a
Malagasy Alkaloid
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Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of
Novel Therapeutic Agents for Cocaine Abuse
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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