Index Catalog // Emory Theses and Dissertations

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Filtern nach: Committee chair name sim Liotta, Dennis C, Emory University Degree PhD

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Part I. Design of a novel class of reversible non-covalent small molecule inhibitors for human Granzyme B (hGrB) Part II. Curcumin and mimics as proteasome inhibitors Part III. Design of novel coactivator binding inhibitors (CBIs) for the estrogen receptor α : break the 1µM barrier

About this Dissertation
Student Name:	Kim, Mi-Sun
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Biochemistry
Department:	Chemistry

Towards the Development of Non-Toxic Therapeutics in the Fight Against Cancer

About this Dissertation
Student Name:	Baillie, Mark
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic and Chemistry, Pharmaceutical
Department:	Chemistry

Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone AnalogsPart II: Discovery of Small Molecule CXCR4 Antagonists

About this Dissertation
Student Name:	Zhan, Weiqiang
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic, Chemistry, Pharmaceutical, and Health Sciences, Oncology
Department:	Chemistry

Computer-Assisted Drug Discovery Part I: Design, Development, Validation and Application of FRESH, a Novel In-Silico High-throughput Screening Program Part II: Monocarbonyl Curcumin Analogues: Heterocyclic Pleiotropic Kinase Inhibitors that Mediate Anticancer Properties Part III: Development of 2nd Generation NAMFIS Software Program by Java

About this Dissertation
Student Name:	Shi, Qi
Date Uploaded:	08/28/2018
Research Field:	Computer Science and Chemistry, Pharmaceutical
Department:	Chemistry

Design, Synthesis and Biological Evaluation of C4-C9 Bridged Epothilone Analogs

About this Dissertation
Student Name:	Jiang, Yi
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic
Department:	Chemistry

Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis, and Biological Evaluation of a Novel Class of Allosteric Modulators of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and Conformational Analysis of Structurally Similar CXCR4 Antagonists

About this Dissertation
Student Name:	Katzman, Brooke M.
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic and Chemistry, General
Department:	Chemistry

Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Modulators

About this Dissertation
Student Name:	Zimmerman, Sommer Shelley
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic
Department:	Chemistry

Design, Synthesis, and Biologic Evaluation of Tetrahydroisoquinoline-Based CXCR4 Modulators

About this Dissertation
Student Name:	Truax, Valarie
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic
Department:	Chemistry

Part 1: Stereoselective Synthesis of Quaternary Center BearingAzetines and β-Amino Acid Derivatives. Part 2: Natural andEnantiomeric Progesterone Analogues for the Treatment of TraumaticBrain Injury

About this Dissertation
Student Name:	MacNevin, Christopher John
Date Uploaded:	08/28/2018
Research Field:	Chemistry, Organic
Department:	Chemistry

Structural Determinants of Activity, Mechanism and Structure Activity Relationships of Novel GluN2C/D Subunit Selective Antagonists of the N-methyl-D-Aspartate Receptor

About this Dissertation
Student Name:	Acker, Timothy Michael
Date Uploaded:	08/28/2018
Research Field:	Chemistry, General and Biology, General
Department:	Biological and Biomedical Sciences