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Design, Development and Application of a Novel In-Silico
High-throughput Screening Approach
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SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM
CARBENOID CHEMISTRY
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
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Development of a novel stereo-selective synthetic route towards
Pumiliotoxin C, potent neurotoxin, via asymmetric
Diels-Alder and sequential protonation-nucleophilic addition as key
reaction steps
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Towards the Development of Non-Toxic Therapeutics in the Fight
Against Cancer
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Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the
Treatment of Hepatitis C Virus
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Use of Furans as Vehicles for Heterocyclic Synthesis: Anaza-Achmatowicz Approach to Piperidine Alkaloids, a Novel OxidativeRoute to Acyloxypyrrolinones, and IMDAF Studies Toward a Synthesisof Minfiensine and Morphine
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Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone AnalogsPart II: Discovery of Small Molecule CXCR4 Antagonists
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Engineering The Substrate Specificity Of Human Deoxycytidine Kinase
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Computer-Assisted Drug Discovery Part I: Design, Development,
Validation and Application of FRESH, a Novel In-Silico
High-throughput Screening Program Part II: Monocarbonyl Curcumin
Analogues: Heterocyclic Pleiotropic Kinase Inhibitors that Mediate
Anticancer Properties Part III: Development of 2nd Generation
NAMFIS Software Program by Java
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