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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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Acylative Redox Dehydration of Carboxylic Acids and Benzoisothiazolones in the Synthesis of Thioesters with Triethylphosphite as a Terminal Reductant
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Development of Fluorescence-based Molecular Tension Probes to Investigate Cellular Mechanical Forces
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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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Part 1: Synthesis and Anti-HIV Activity of Novel CyclobutylNucleoside and Nucleotide Analogs, Part 2: Synthesis of FluorescentNucleoside Analogs, Part 3: Synthesis of Abacavir
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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Towards the Synthesis of Marine Polyether Triterpenes
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
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Part I: Synthesis of Cyclobutyl Nucleoside and NucleotideAnalogues as HIV-1 Reverse Transcriptase InhibitorsPart II: Improvement of Glycosylation Regioselectivity in PurineNucleoside Analogue SynthesisPart III: Enantioselective Synthesis ofβ-D-Dioxolane-T andβ-D-FDOC
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Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions
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Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin
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Part I: Conformational Analysis of Bioactive Molecules inSolutionPart II: Structure-Based Design of Selective Inhibitors ofCyclin-Dependent Kinase 7
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Computational Studies of Ligand Protein Interactions Part I: TheT-Taxol Conformation Part II: Elucidating Interdependent BindingSites on Tubulin
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Synthesis of Those Sectors of Saccharomicin A and B ContainingSaccharosamine and the Discovery of a Novel 4-H-1,3-OxazineSynthesis
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Part 1: Stereoselective Synthesis of Quaternary Center BearingAzetines and β-Amino Acid Derivatives. Part 2: Natural andEnantiomeric Progesterone Analogues for the Treatment of TraumaticBrain Injury
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Synthesis and Characterization of Unusal Amphiphiles Part I. Nonsteroidal Facial Amphiphiles Part II. Diketopiperazine Derived Surfactants
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Engineering The Substrate Specificity Of Human Deoxycytidine Kinase
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Part I: Design, Synthesis and Biological Evaluation of C6-C8 Bridged Epothilone AnalogsPart II: Discovery of Small Molecule CXCR4 Antagonists
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Use of Furans as Vehicles for Heterocyclic Synthesis: Anaza-Achmatowicz Approach to Piperidine Alkaloids, a Novel OxidativeRoute to Acyloxypyrrolinones, and IMDAF Studies Toward a Synthesisof Minfiensine and Morphine
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Potential Cross-Talk between the Aryl Hydrocarbon Receptor (AHR)
and the Constitutive Androstane Receptor (CAR)
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Design, Development and Application of a Novel In-Silico
High-throughput Screening Approach
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SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM
CARBENOID CHEMISTRY
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
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Development of a novel stereo-selective synthetic route towards
Pumiliotoxin C, potent neurotoxin, via asymmetric
Diels-Alder and sequential protonation-nucleophilic addition as key
reaction steps
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Optimization of Dual-tropic CXCR4/CCR5 HIV-1 Entry Inhibitors and a
Market Analysis
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Towards the Development of Non-Toxic Therapeutics in the Fight
Against Cancer
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Synthetic Studies Toward Cyclobutyl Nucleoside Analogs for the
Treatment of Hepatitis C Virus
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Incorporating Transition Metal Organometallic Chemistry into the
Introductory Organic Chemistry Course
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Computer-Assisted Drug Discovery Part I: Design, Development,
Validation and Application of FRESH, a Novel In-Silico
High-throughput Screening Program Part II: Monocarbonyl Curcumin
Analogues: Heterocyclic Pleiotropic Kinase Inhibitors that Mediate
Anticancer Properties Part III: Development of 2nd Generation
NAMFIS Software Program by Java
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Design, Synthesis and Biological Evaluation of C4-C9 Bridged
Epothilone Analogs
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Navigating the Roads to Drug Discovery: Part 1: Design, Synthesis,
and Biological Evaluation of a Novel Class of Allosteric Modulators
of N-Methyl-D-Aspartate Receptor Function Part 2: Discovery of
Novel Tetrahydroisoquinoline (THIQ)-Based CXCR4 Antagonists and
Conformational Analysis of Structurally Similar CXCR4 Antagonists
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Generating designer enzymes for therapeutic and industrial
applications
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Application of fluorescent nucleoside analogs in direct evolution
of Drosophila melanogaster deoxyribonucleoside kinase
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Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Modulators
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Design, Synthesis, and Biologic Evaluation of
Tetrahydroisoquinoline-Based CXCR4 Modulators
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Organometallic Enantiomeric Scaffolds in the Synthesis of
Alkaloids: I. Homo-SN2´-like Reaction/Annulative Demetallation
and the Application in the Synthesis of (+)-Isofebrifugine II.
Uncatalyzed Electrophilic C-C Bond Forming Reactions of Pyranyl and
Pyridinyl Molybdenum Complexes
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ASYMMETRIC REACTIONS OF DONOR/ACCEPTOR RHODIUM CARBENOIDS: FROM
FORMAL CYCLOADDITIONS TO C-H INSERTION
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Tumor Necrosis Factor-alpha mediated transactivation of the
Epidermal Growth Factor Receptor and Keratinocytes
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Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Antagonists
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Progress Toward a Common Intermediate for C1 Modified
Enigmols
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Rhodium Alkenylcarbenes: Novel Reactivity and Precursors
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Validation of Receptor-Based Drug Design and Applications in the
Study of IKKs, Truncated Taxane and LRH-1
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Part I: Design, Synthesis, and Biological Activity of NMDA
Receptor Antagonists
Part II: Design and Synthesis of Measles Virus Inhibitors
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SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID
REACTIONS
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Development of Monocarbonyl Curcumin Analogues Towards Treating
Tuberculosis and Cancer
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Progress Toward the Total Synthesis of PM-toxin A And Future
Development of Mild Lewis Acid Activated Alkynylation of Epoxides
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Use of Receptor-Based Drug Design and Applications in the Study
of finding antagonists for MD-2/TLR4, GLP and CXCR4
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