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Liotta, Dennis C, Emory University
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Year
2012
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Potential Cross-Talk between the Aryl Hydrocarbon Receptor (AHR)
and the Constitutive Androstane Receptor (CAR)
1 of 10
Design, Development and Application of a Novel In-Silico
High-throughput Screening Approach
2 of 10
Multi-mechanism antiretroviral approach targeting macrophage
derived viral sanctuaries
3 of 10
SYNTHESIS OF SMALL MOLECULE THERAPEUTICS UTILIZING RHODIUM
CARBENOID CHEMISTRY
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Part I. Design of a novel class of reversible non-covalent small
molecule inhibitors for human Granzyme B (hGrB)
Part II. Curcumin and mimics as proteasome inhibitors
Part III. Design of novel coactivator binding inhibitors (CBIs)
for the estrogen receptor α : break the 1µM barrier
5 of 10
Development of a novel stereo-selective synthetic route towards
Pumiliotoxin C, potent neurotoxin, via asymmetric
Diels-Alder and sequential protonation-nucleophilic addition as key
reaction steps
6 of 10
SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID
REACTIONS
7 of 10
Screening, hit expansion and mechanistic studies for natural
product analogs derived from traditional herbal medicine: curcumin
and triptolide.
8 of 10
Use of Receptor-Based Drug Design and Applications in the Study
of finding antagonists for MD-2/TLR4, GLP and CXCR4
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Design, Synthesis, and Biological Evaluation of Subunit
Selective N-Methyl-D-Aspartate Receptor Modulators
10 of 10