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Part I: Measles virus entry into cells and the inhibition offusion and replicationPart II: The nature of cyclostreptin's interaction withmicrotubules
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Part 1: Synthesis and Anti-HIV Activity of Novel CyclobutylNucleoside and Nucleotide Analogs, Part 2: Synthesis of FluorescentNucleoside Analogs, Part 3: Synthesis of Abacavir
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Design, Synthesis, and Biological Evaluation of Subunit
Selective N-Methyl-D-Aspartate Receptor Modulators
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Chapter 1. Total synthesis of Fumonisin B1 Chapter 2.
Synthesis of Unnatural Sphingolipids: 1-deoxy-5-hydroxysphinganine
and its diastereomers Chapter 3. Development of Methodology:
Synthesis of cis- and trans-homoallylic alcohols
Chapter 4. Human Milk Oligosaccharides: Synthesis of Natural and
Unnatural oligomers
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Investigation and Modeling of Binding Modes of Novel Small-Molecule
Nox2 Inhibitors
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I. A New Approach to the Synthesis of a Key 5-Oxo-Pyridinyl
Molybdenum Scaffold. II. Oxidative Demetalation of
η3-Allylmolybdenum Complexes with an Oxygen
Nucleophile; Application to the Synthesis of (+)-Isofebrifugine
Analogs
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Paclitaxel and Cyclostreptin in theTubulin Binding Site
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The Design, Synthesis, and Biological Evaluation of Subunit-selective N-Methyl-D-Aspartate Receptor Potentiators
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Towards the Synthesis of Marine Polyether Triterpenes
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Acylative Redox Dehydration of Carboxylic Acids and Benzoisothiazolones in the Synthesis of Thioesters with Triethylphosphite as a Terminal Reductant
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Part I: Synthesis of Cyclobutyl
Nucleoside Analogs That Mimic AZT for Inhibition of the K65R HIV-1
Reverse Transcriptase Mutant
Part II: Synthesis and Evaluation of
Truncated Triptolide Analogs to Suppress Chronic Inflammation
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Analysis of the EF24-modulated signaling pathways for thedevelopment of novel cancer combination therapies
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Identification of Small Molecule Inhibitors of I-κB
Kinase
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Part 1. Discovery of a Fluorinated Enigmol Analog with Enhanced Pharmacokinetic and Anti-Tumor Properties. Part 2. Preferential Activation of Metabotropic Glutamate Receptor 3 over Metabotropic Glutamate Receptor 2
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Expanding the Scope of Donor/Acceptor Carbenes and the Synthesis of
Novel Therapeutic Agents for Cocaine Abuse
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Incorporating the Scientific Contributions of Research Faculty into
the Chemical Education of Undergraduate Students at Emory
University
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Development of a Copper Catalyzed Aminoacetoxylation Reaction of
Olefins, Development of an Intermolecular and Diastereoselective
Iminium Cascade Reaction and Studies Towards the Synthesis of a
Malagasy Alkaloid
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Discovery and Synthesis of Next Generation Chemokine Modulators with or without Concurrent HIV Reverse Transcriptase Inhibitory Activity
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Synthesis of 2'-Fluoro-2',3'-Dideoxynucleosides as Inhibitors of
Hepatitis C Virus RNA-Dependent RNA Polymerase; Synthesis of
Cyclobutyl Phosphonate and Phosphoramidate Prodrugs for Inhibition
of HIV Reverse Transcriptase
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Part I: Structure and Function in the NMDA Ligand Binding DomainPart II: Comparison of Paclitaxel Analogs through MolecularDynamics Simulation; Solution Conformations of Cyclic Peptides
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Chapter 1: The development of a model system for the B-ring of
brevenal and methods for the formation of seven-membered rings.
Chapter 2: Iterative alkyne-epoxide cross-couplings toward the
total synthesis of PM toxin A. Chapter 3: The development of
synthons for 1,3-dimethylallylation of aldehydes.
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Synthesis and Anti-Viral Activity of Novel 3,6-dioxa-[3.2.0]bicyclonucleoside Nucleotide Analogs
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Investigation of C-H Bond Oxidation Reactions: I. Asymmetric
Amination of C-H Bonds Using Ruthenium(II) Catalysts II.
Investigation of Structural Determinants of Monoamine Oxidase B
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Part I: Synthesis of Cyclobutyl Nucleoside and NucleotideAnalogues as HIV-1 Reverse Transcriptase InhibitorsPart II: Improvement of Glycosylation Regioselectivity in PurineNucleoside Analogue SynthesisPart III: Enantioselective Synthesis ofβ-D-Dioxolane-T andβ-D-FDOC
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Use of Receptor-Based Drug Design and Applications in the Study
of finding antagonists for MD-2/TLR4, GLP and CXCR4
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Screening, hit expansion and mechanistic studies for natural
product analogs derived from traditional herbal medicine: curcumin
and triptolide.
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Metal Mediated Cross-Coupling Reactions for Carbon-Carbon andCarbon-Nitrogen Bonds Formation under Neutral pH Conditions
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Synthesis of Altromycin and Kidamycin Aglycones from a Common Intermediate & Studies towards the Total Synthesis of Kidamycin
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Progress Toward the Total Synthesis of PM-toxin A And Future
Development of Mild Lewis Acid Activated Alkynylation of Epoxides
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SYNTHESIS OF CYCLOPROPANES AND DIHYDROFURANS BY METAL CARBENOID
REACTIONS
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Part I: Design, Synthesis, and Biological Activity of NMDA
Receptor Antagonists
Part II: Design and Synthesis of Measles Virus Inhibitors
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Development of Monocarbonyl Curcumin Analogues Towards Treating
Tuberculosis and Cancer
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Inhibition of the NF-κB signaling pathway by the curcumin
analogs, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31) and
3,5-Bis(2-pyridinylmethylidene)-1-methyl-4-piperidone (UBS109):
in-vitro and in-vivo studies.
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Part I: Conformational Analysis of Bioactive Molecules inSolutionPart II: Structure-Based Design of Selective Inhibitors ofCyclin-Dependent Kinase 7
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Rhodium Alkenylcarbenes: Novel Reactivity and Precursors
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Validation of Receptor-Based Drug Design and Applications in the
Study of IKKs, Truncated Taxane and LRH-1
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Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Antagonists
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Progress Toward a Common Intermediate for C1 Modified
Enigmols
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Computational Studies of Ligand Protein Interactions Part I: TheT-Taxol Conformation Part II: Elucidating Interdependent BindingSites on Tubulin
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Synthesis of Those Sectors of Saccharomicin A and B ContainingSaccharosamine and the Discovery of a Novel 4-H-1,3-OxazineSynthesis
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Tumor Necrosis Factor-alpha mediated transactivation of the
Epidermal Growth Factor Receptor and Keratinocytes
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Structural Determinants of Activity, Mechanism and Structure
Activity Relationships of Novel GluN2C/D Subunit Selective
Antagonists of the N-methyl-D-Aspartate Receptor
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Part 1: Stereoselective Synthesis of Quaternary Center BearingAzetines and β-Amino Acid Derivatives. Part 2: Natural andEnantiomeric Progesterone Analogues for the Treatment of TraumaticBrain Injury
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ASYMMETRIC REACTIONS OF DONOR/ACCEPTOR RHODIUM CARBENOIDS: FROM
FORMAL CYCLOADDITIONS TO C-H INSERTION
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Organometallic Enantiomeric Scaffolds in the Synthesis of
Alkaloids: I. Homo-SN2´-like Reaction/Annulative Demetallation
and the Application in the Synthesis of (+)-Isofebrifugine II.
Uncatalyzed Electrophilic C-C Bond Forming Reactions of Pyranyl and
Pyridinyl Molybdenum Complexes
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Design, Synthesis, and Biologic Evaluation of
Tetrahydroisoquinoline-Based CXCR4 Modulators
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Development of Fluorescence-based Molecular Tension Probes to Investigate Cellular Mechanical Forces
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Synthesis and Characterization of Unusal Amphiphiles Part I. Nonsteroidal Facial Amphiphiles Part II. Diketopiperazine Derived Surfactants
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Design, Synthesis, and Biological Evaluation of Subunit-Selective
N-Methyl-D-Aspartate Receptor Modulators
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Application of fluorescent nucleoside analogs in direct evolution
of Drosophila melanogaster deoxyribonucleoside kinase
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