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A Generalized Approach to Deliver Functionalized Isoindolines in Macrocycles
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Developing Transition Metal Catalysts that Incorporate Redox-Active Ligand Frameworks for Sustainable Catalysis
2 of 100
Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
3 of 100
Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
4 of 100
DNA mechanocapsules: Force responsive tetrahedral DNA nanostructures with modular cargo delivery for targeting mechanical phenotypes of diseases
5 of 100
Metal Catalyst Methodology Development towards Carbon-Oxygen Bond Formation: Synthesis of Vinyl Ethers and Vinyl Esters
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The Development of Planar Chiral Indenyl Catalysts and the Progress Towards Synthesis of the Western Macrocycle of Darobactin A
7 of 100
Group IX Metal-Catalyzed C–H Activation Towards the Development of New Synthetic Strategies
8 of 100
Natural Product Inspired Complementary Approaches to Counter Antimicrobial Resistance: Synthetic and Biological Investigations of Antibacterial Small Molecules
9 of 100
An Investigation on the Diastereoselectivity of α-Methylstyrene Cyclopropanations Catalyzed by Dirhodium (II) Catalysts
10 of 100
Synthesis of Novel Nucleotide Tenofovir/Lamivudine Prodrug Conjugates for treatment of Human Immunodeficiency Virus and Hepatitis B
11 of 100
Synthesis and Evaluation of Novel Phenyl-Adamantane Dirhodium Catalyst for C-H Functionalization
12 of 100
New Advances in Asymmetric Cyclopropanation and Drug Discoveries Using Dirhodium(II) Tetracarboxylates
13 of 100
Asparagine and Glutamine Bioconjugation
14 of 100
Synthesis of alkyl analogues of 1,4-dihydropyridine for developing novel treatment against chemoresistance in prostate cancer
15 of 100
Carboxylation of C(sp2) Bromides Enabled by Metallophotoredox Dual Catalysis and Sodium Formate
16 of 100
Computational Modeling of Oxyradical and Metal-Oxo Reactivity and Selectivity in Hydrogen Atom Transfer Reactions
17 of 100
Triazene Coarctate Cyclization for the Synthesis of Fluorescent Cyclic Peptides
18 of 100
Overcoming Antibacterial Resistance through Synthesis of Small Molecules Targeting Efflux Mechanisms
19 of 100
Overcoming the Limitations of Rhodium-Catalyzed Asymmetric Cyclopropanation and Other Adventures in Strained Ring Synthesis
20 of 100
Catalytic Process for Epoxide Ring-Opening with Terminal Alkynes for Carbon-Carbon Bond Formation
21 of 100
Novel Quaternary Ammonium Compounds Derived from the Antimicrobial Natural Product Ianthelliformisamine C
22 of 100
Cu- and Pd-Catalyzed a-Hydroxycyclopropanol Ring Opening Reactions: Electrophilic Trappings to 3-Furanones, and Carbonylation to 4-Ketovalerolactones.
23 of 100
Radical Reactivity via Transient Carbon Dioxide Radical Anion (CO2•−)
24 of 100
Design and Synthesis of Chemical Modulators for Altered Activity of Nuclear Receptor Liver Receptor Homolog-1 and Synthesis of Spirocyclic Piperidines via Radical Hydroarylation
25 of 100
Chemo and Site Selective Modification of Proteins and Chemical Tools for Studying Mono-Methyl Lysine (Kme)
26 of 100
Developing Chemical Tools for Selective Peptide Modification
27 of 100
Studies in Small Molecule Drug Discovery: Part I. Synthesis of Novel Nucleoside-Based Antivirals to Treat Hepatitis C; Part II. Validation and Implementation of a Machine Learning Algorithm to Create a Safer Kinase Inhibitor as a Potential First-in-Class Antiparkinsonian Agent
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Membranes & Metals: Bacterial Targets to Fight Antibiotic Resistance
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Exploration of Bilingual Peptide Nucleic Acids
30 of 100
Development of Chemical Methods for Labeling Monomethyl Lysine Post-Translational Modification and Serine and their Applications.
31 of 100
A Three-Pronged Approach to Combatting Antibiotic Resistance
32 of 100
Synthesis and Biological Investigation of Membrane-targeting Antimicrobials
33 of 100
Synthesis and Biological Investigation of Natural Product-Inspired Antimicrobial Compounds
34 of 100
Fibrinogen and Clotting Characterization in COVID-19 Patients
35 of 100
Synthetic Investigations into Small Molecules with Antibacterial Potential
36 of 100
Site-Selective and Enantioselective C-H Functionalization of Unactivated C–H Bonds in the Presence of Nitrogen Functionality
37 of 100
Synthesis of Novel EP2 Prostaglandin Antagonists for Optimal Blood-Brain Barrier Permeation as Radioligands
38 of 100
Computational Development of Macrocyclic Drug Hits and Synthetic Strategy towards Peptide Macrocyclization
39 of 100
Leveraging Chemical Tools to Target Bacterial Membranes and Combat Antimicrobial Resistance
40 of 100
Asymmetric Rhodium(II)-Carbene C-H Functionalization: A Complementary Tool To Synthetic Disconnection Strategies
41 of 100
Glyoxal-based Caging of Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Viral Infections
42 of 100
Total synthesis and biological investigations of natural product inspired antimicrobials
43 of 100
C-H Functionalization Inspired Total Synthesis and New Donor/Acceptor Carbenes for Asymmetric C-H Functionalization
44 of 100
Leveraging Organic Synthesis to Disrupt and Understand Essential Bacterial Processes
45 of 100
Practical Application and In Situ Kinetic Studies of Dirhodium(II) Tetracarboxylate Catalyzed Carbene Reactions
46 of 100
Targeting Bacterial Tolerance and Resistance with Small Molecules
47 of 100
Design, Synthesis, and Utility of Group IX Metal Catalysts for C–H Functionalization
48 of 100
Dearomative Photocatalytic Hydroalkylation and Lipophilic Prodrugs
49 of 100
A Tale of Two Chemistries: Dynamics of Delay-Coupled Belousov-Zhabotinsky Oscillators; TrkB Activators: A Review; Synthesis of TrkB Agonists
50 of 100
Cobalt Catalyzed Intramolecular Cyclization of Acyclic Alkenols for Polycyclic Ether Synthesis
51 of 100
EXPANDING THE SCOPE AND APPLICATION OF N-SULFONYL-1,2,3-TRIAZOLES AS ALTERNATE PRECURSORS TO DONOR/ACCEPTOR RHODIUM CARBENES
52 of 100
Arene Dearomatization via Radical Hydrofunctionalization
53 of 100
Design and Synthesis of a PD-L1 Radioligand for Diagnostic Imaging and Development and Optimization of a Potent Liver Receptor Homolog-1 Agonist
54 of 100
The Iterative Design of Aptamer-Functionalized Membranes to Enable Detection, Sequestration, and Recovery of Small-Molecule Compounds
55 of 100
Intercepting Photochemically Generated Aminoalkyl and Aryl Radical Intermediates to Access Complexity Quickly
56 of 100
Developing First-Row Transition Metal Complexes for Green Catalytic C–H Activation and Oxidations
57 of 100
GluN2C/D subunit selective antagonist for NMDARs: 997 Series
58 of 100
Optimization of Rh2(S-TPPTTL)4 Through Ligand Diversification
59 of 100
Unusual Paradigms in Selective Synthesis: Part 1: Toward the Synthesis of Racemic and Enantioenriched HIOC; Part 2: Fluorinated Alcohols: Powerful Promoters for the Ring-Opening Reactions of Epoxides with Carbon Nucleophiles
60 of 100
Probing Bacterial Mechanisms via Small Molecule Antibiotics
61 of 100
Design and Synthesis of New Liver Receptor Homolog-1 Modulators and Probes
62 of 100
The Development and Mechanistic Studies of Group(IX)Cp*-Catalyzed Allylic C–H Functionalization Reactions Proceeding via a π-allyl Intermediate
63 of 100
Studies Towards the Synthesis of Malagasy Alkaloids, and Development and Applications of Regio- and Enantioselective Group IX Metal-Catalysed Reactions
64 of 100
Structural Requirements of the Sulfonyl Prolinate Ligands for Dirhodium Catalysis
65 of 100
Computational and Experimental Studies of Selective Rhodium-Catalyzed Allylic C–H Functionalization through π-Allyl Intermediates and Computational Development of Macrocycle Leads for Undruggable Targets
66 of 100
Harnessing the Dual Nature of Peptide Nucleic Acids
67 of 100
Broadening the applications of rhodium donor/acceptor carbene mediated C–H functionalization
68 of 100
Allylic C-H Arylation, Enantioselective Catalyst Development, and Enantioselective Allylic C-H Amidation
69 of 100
Exploring the Influence of Dirhodium Catalyst Structure on the Regio- and Stereoselectivity Properties of Donor/Acceptor Carbenes
70 of 100
Development and Applications of a New Dirhodium(II) Tetracarboxylate Catalyst and Asymmetric Cyclopropanation of Heterocyclic Compounds
71 of 100
Investigation of the Bridgehead Substituent of the Leading LRH-1 Agonists
72 of 100
Radical Conjugate Addition of N-Heterocycles and Tertiary Amines
73 of 100
Synthetic Applications of Dirhodium(II) Catalysis
74 of 100
Development and Optimization of Monosubstituted and Disubstituted Alkene Synthesis for Future Intramolecular Alkene Hydroalkoxylation Reactions
75 of 100
Modification of Quorum Quenching Analogs from Schinus terebinthifolia Fruit Extract
76 of 100
Synthesis of a Click-Compatible Phenylacrylamide to Probe A-to-I RNA Editing
77 of 100
Synthesis of a novel C-nucleoside prodrug for treatment of Hepatitis B
78 of 100
Allylic C-H Functionalization Studies on Allylbenzene Derivatives
79 of 100
Development of Intermolecular Couplings of Aryl Radical Species with Olefins
80 of 100
Reductive Processes Enabled by Photoredox for the Synthesis and Modification of Pharmaceutically Relevant Molecules
81 of 100
Synthesis, Structure-Activity Relationship, and Biological Evaluation of Subunit-Selective NMDA Receptor Modulators
82 of 100
Carolacton and Honokiol: using natural product inspiration to target the oral microbiome
83 of 100
Computational and Experimental Studies of Allylic C-H Functionalization of Internal Olefins via Group IX Metal-Pi-Allyl Intermediates and Invention of a Chiral Indenylrhodium(III) Catalyst
84 of 100
Structure, Synthesis, and Reactivity: Intentional Design Approaches to Agonists for Liver Receptor Homolog-1 and Photochemical Arene Dearomatization
85 of 100
Complementary Approaches to Combat Antibacterial Resistance: Metal-binding Small Molecules and Quaternary Ammonium Compounds
86 of 100
Radical Spirocyclization via Organic Photoredox Catalysis
87 of 100
The Synthesis and Application of a Series of C4-Symmetric Dirhodium Catalysts Derived from 1-(2-Chlorophenyl)-2,2-Diphenylcyclopropanecarboxylate Ligands
88 of 100
The Development of Complementary Allylic C-H Amination and Amidation Conditions for the Regioselective Functionalization of Group IX MCp*-π-Allyl Intermediates
89 of 100
Synthesis of bulky 1,4,7-triazacylcononanes, including asymmetric derivatives; Esterification by aryl-diselenide catalyzed redox condensation; 1-amino-3,4-difluorocyclopentane-1-carboxylic acids as PET imaging agents
90 of 100
Synthesis of 18F-PET-sensitive Agents for Targeted Visualization of Brain Tumors
91 of 100
Modification of Tetrahydroisoquinoline-and-Mopholine-Containing CXCR4 Antagonists with Morpholine Analogs
92 of 100
Allylic C-H Functionalization of Disubstituted Olefins via Rhodium-π-Allyl Intermediates and Development of a Chiral Cyclopentadienyl Catalyst
93 of 100
The Control of Stereoselectivity and Regioselectivity both in Intramolecular and Intermolecular Carbon-Oxygen Bond-Forming Reactions
94 of 100
In Situ Kinetic Studies on Rhodium (II) Carboxylate Catalysts with Cyclopropanation Reactions
95 of 100
The Design, Synthesis, and Biological Evaluation of Subunit-Selective Modulators of the N-Methyl-D-Aspartate Receptor
96 of 100
Promysalin and CD437: Compounds Investigating New Antibacterial Mechanisms
97 of 100
Strategies to Develop Antibiotics via Diversification from Natural Products
98 of 100
Progress toward Lewis acid catalyzed asymmetric transformation
of amino alcohols towards influence on the Blakey group synthesis
of malagashanine
99 of 100
Synthesis Towards a Constrained Paclitaxel Analog
100 of 100