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Advancing novel ligand-based cellular therapies for the treatment of pediatric acute myeloid leukemia
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Proteomic and transcriptomic signatures of microglia-derived extracellular vesicles and extension into in vivo systems.
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Identifying HELZ as a Novel DNA Double-Strand Break Repair Protein
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Astrocyte Primary Cilia are Dynamic during Development
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Investigating the Impact of Soat1 Knock-Out on Visceral Adipose Tissue Regulatory T-Cell Accumulation in TCR Transgenic Mice.
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Small-Molecule Tools to Probe and Modulate RNA Function
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Proteomic profiling of neuronal and microglial cells using TurboID in inflammatory and homeostatic states for extension into in vivo systems.
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MERTK inhibition selectively activates a DC – T-cell axis to provide anti-leukemia immunity
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The Yes-Associated Protein (YAP) promotes resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1
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The development and functional testing of cellular therapies against protein tyrosine kinase 7 (PTK7) to treat high-risk neuroblastoma
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Local ecdysone synthesis in a wounded epithelium sustains developmental delay and promotes regeneration in Drosophila
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Intoxicating Interactions: The Impacts of Chronic Alcohol Use and SARS-CoV-2 Infection on Airway Epithelial Cells
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Ectopic transcription due to inappropriately inherited histone methylation may interfere with the ongoing function of terminally differentiated cells
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Investigating the Role for Y-Box Binding Protein 1 in Medulloblastoma Radiation Resistance and Post-transcriptional Regulation of Migration and Metastasis
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The Mitochondrial Electron Transport Chain Regulates Expression and Secretion of the Lipoprotein APOE
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Succinyl-CoA ligase ADP-forming subunit beta promotes stress granule assembly to regulate redox and drive cancer metastasis
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The Effect of Two Experimental Treatments (R13 & Compound 11) on Sensory Axon Regeneration After Peripheral Nerve Injury
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Investigating the role of SAMHD1 in response to Camptothecin and Sacituzumab Govitecan in triple-negative breast cancer cell line MDA-MB-231
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Impact of cytokines/chemokines on epigenetic modifications in immune cells isolated from healthy Down syndrome individuals
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Opto-Chemogenetic Modulation of Astrocytic Buffering for Re-Establishing Neuronal Homeostasis
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Analysis of Factors Required for Centrocortin mRNA Localization to Centrosomes in Drosophila Embryos
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The loss of H3T45 phosphorylation enhances histone deacetylase (HDAC) recruitment to histone H3 in hormone receptor-positive, PI3K-activated breast cancer
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The Role of Sox7 on the WNT Signaling Pathway in Lung Adenocarcinoma
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Evolution of Centromeric Protein Coding Genes in the Mus Genus
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A Taxonomic Approach to Understanding Diet-Induced Changes in Mouse Fecal and Ileal Immunoglobulin A (IgA) Concentrations
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Analyzing the localization of LSD1 in Tau transfected HEK293 cells: a novel method for exploring biological mechanisms of tauopathy and potential therapeutics
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Structural interactions of human respiratory syncytial virus NS2 with human innate immune system receptors RIG-I and MDA5
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Localization of mRNAs to Centrosomes Requires the Pericentriolar Material Scaffold
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Understanding drivers of doxorubicin resistance in Atypical Teratoid Rhabdoid Tumor
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In Vitro Expansion of Murine γδ T Cells and Transfection of Human γδ T cells for CAR T Cell Therapy
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Characterization of HIV-1 antisense RNA and enhanced transcription with interference of LEDGF/p75-directed integration
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Characterization of Cultured Human Erythrocytes Derived from BMI-1 Transduced Erythroblasts: Towards an Alternate Blood Supply
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Medulloblastoma Circulating Tumor Cell Clusters as a Novel Tumor Biomarker and Mechanism for Hematogenous Spread
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Evaluating Efficacy of CD26+ CAR T Cells in an Orthotopic, Immunocompetent Mouse Model of Pancreatic Ductal Adenocarcinoma
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Developing a Method for Circulating Tumor Cell Detection in Pediatric Medulloblastoma: Correlations with Metastatic Status and Prognostic Factors
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The Role of Fibro/Adipogenic Progenitors for Tongue Muscle Remodeling by High-Fat Diet
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YB-1 Promotes PLXND1 mRNA Translation to Mediate Tumor Migration in Sonic Hedgehog Medulloblastoma
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Effects of Phosphate Uptake/Metabolism on Behavior of Lung Cancer Cells
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Investigation of mitochondrial fusion-mediated T cell expansion and persistence for cancer immunotherapy applications
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Development and characterization of synthetic modulators of nuclear receptor LRH-1: Driving divergent signaling using a common molecular scaffold
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Imatinib mesylate as a host directed therapeutic for mycobacterial infection
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Differential regulation of Peroxisome Proliferator Activating Receptors (PPARs) via host and microbial derived processes
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Roles for Bile Transporters in the Pathogenesis and Treatment of Liver and Intestinal Diseases
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CD8 T cell Activation In Cancer Is Comprised Of Two Distinct Phases
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MEK inhibition mediates immunomodulatory factors and cell populations in advanced biliary tract cancer
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Understanding and Optimizing Gamma-Delta T cells as a Platform for Cellular Immunotherapies
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Delineating How Aging- and Obesity-Associated Chronic Inflammation Impacts B-cell Acute Lymphoblastic Leukemia Progression
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Regulation of Leukocyte Inflammation by Small Particles Including Extracellular Vesicles and Viruses
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Translational studies of neutrophils, macrophages, and T cells in the human lung: implications for cystic fibrosis and other chronic respiratory pathologies
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Characterization of cell death in Casp3-deficient mouse embryonic fibroblasts
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