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A Generalized Approach to Deliver Functionalized Isoindolines in Macrocycles
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Developing Transition Metal Catalysts that Incorporate Redox-Active Ligand Frameworks for Sustainable Catalysis
2 of 100
Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
3 of 100
DNA mechanocapsules: Force responsive tetrahedral DNA nanostructures with modular cargo delivery for targeting mechanical phenotypes of diseases
4 of 100
Group IX Metal-Catalyzed C–H Activation Towards the Development of New Synthetic Strategies
5 of 100
Development of New Diaryl Diazo Compounds and the Study of their application in C-H Functionalization Chemistry
6 of 100
Metal Catalyst Methodology Development towards Carbon-Oxygen Bond Formation: Synthesis of Vinyl Ethers and Vinyl Esters
7 of 100
The Development of Planar Chiral Indenyl Catalysts and the Progress Towards Synthesis of the Western Macrocycle of Darobactin A
8 of 100
Natural Product Inspired Complementary Approaches to Counter Antimicrobial Resistance: Synthetic and Biological Investigations of Antibacterial Small Molecules
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Overcoming the Limitations of Rhodium-Catalyzed Asymmetric Cyclopropanation and Other Adventures in Strained Ring Synthesis
10 of 100
Overcoming Antibacterial Resistance through Synthesis of Small Molecules Targeting Efflux Mechanisms
11 of 100
Radical Reactivity via Transient Carbon Dioxide Radical Anion (CO2•−)
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Design and Synthesis of Chemical Modulators for Altered Activity of Nuclear Receptor Liver Receptor Homolog-1 and Synthesis of Spirocyclic Piperidines via Radical Hydroarylation
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An Investigation on the Diastereoselectivity of α-Methylstyrene Cyclopropanations Catalyzed by Dirhodium (II) Catalysts
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Synthesis of Novel Nucleotide Tenofovir/Lamivudine Prodrug Conjugates for treatment of Human Immunodeficiency Virus and Hepatitis B
15 of 100
Synthesis and Evaluation of Novel Phenyl-Adamantane Dirhodium Catalyst for C-H Functionalization
16 of 100
New Advances in Asymmetric Cyclopropanation and Drug Discoveries Using Dirhodium(II) Tetracarboxylates
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Asparagine and Glutamine Bioconjugation
18 of 100
Synthesis of alkyl analogues of 1,4-dihydropyridine for developing novel treatment against chemoresistance in prostate cancer
19 of 100
Carboxylation of C(sp2) Bromides Enabled by Metallophotoredox Dual Catalysis and Sodium Formate
20 of 100
Computational Modeling of Oxyradical and Metal-Oxo Reactivity and Selectivity in Hydrogen Atom Transfer Reactions
21 of 100
Triazene Coarctate Cyclization for the Synthesis of Fluorescent Cyclic Peptides
22 of 100
Catalytic Process for Epoxide Ring-Opening with Terminal Alkynes for Carbon-Carbon Bond Formation
23 of 100
Novel Quaternary Ammonium Compounds Derived from the Antimicrobial Natural Product Ianthelliformisamine C
24 of 100
Cu- and Pd-Catalyzed a-Hydroxycyclopropanol Ring Opening Reactions: Electrophilic Trappings to 3-Furanones, and Carbonylation to 4-Ketovalerolactones.
25 of 100
Probing Bacterial Mechanisms via Small Molecule Antibiotics
26 of 100
Asymmetric Rhodium(II)-Carbene C-H Functionalization: A Complementary Tool To Synthetic Disconnection Strategies
27 of 100
Chemo and Site Selective Modification of Proteins and Chemical Tools for Studying Mono-Methyl Lysine (Kme)
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Developing Chemical Tools for Selective Peptide Modification
29 of 100
Studies in Small Molecule Drug Discovery: Part I. Synthesis of Novel Nucleoside-Based Antivirals to Treat Hepatitis C; Part II. Validation and Implementation of a Machine Learning Algorithm to Create a Safer Kinase Inhibitor as a Potential First-in-Class Antiparkinsonian Agent
30 of 100
Membranes & Metals: Bacterial Targets to Fight Antibiotic Resistance
31 of 100
Design and Synthesis of a PD-L1 Radioligand for Diagnostic Imaging and Development and Optimization of a Potent Liver Receptor Homolog-1 Agonist
32 of 100
Synthesis of Novel EP2 Prostaglandin Antagonists for Optimal Blood-Brain Barrier Permeation as Radioligands
33 of 100
Allylic C-H Arylation, Enantioselective Catalyst Development, and Enantioselective Allylic C-H Amidation
34 of 100
Total synthesis and biological investigations of natural product inspired antimicrobials
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Exploration of Bilingual Peptide Nucleic Acids
36 of 100
Development of Chemical Methods for Labeling Monomethyl Lysine Post-Translational Modification and Serine and their Applications.
37 of 100
A Three-Pronged Approach to Combatting Antibiotic Resistance
38 of 100
Synthesis and Biological Investigation of Membrane-targeting Antimicrobials
39 of 100
Fibrinogen and Clotting Characterization in COVID-19 Patients
40 of 100
Harnessing the Dual Nature of Peptide Nucleic Acids
41 of 100
Computational and Experimental Studies of Selective Rhodium-Catalyzed Allylic C–H Functionalization through π-Allyl Intermediates and Computational Development of Macrocycle Leads for Undruggable Targets
42 of 100
Studies Towards the Synthesis of Malagasy Alkaloids, and Development and Applications of Regio- and Enantioselective Group IX Metal-Catalysed Reactions
43 of 100
Leveraging Chemical Tools to Target Bacterial Membranes and Combat Antimicrobial Resistance
44 of 100
C-H Functionalization Inspired Total Synthesis and New Donor/Acceptor Carbenes for Asymmetric C-H Functionalization
45 of 100
Practical Application and In Situ Kinetic Studies of Dirhodium(II) Tetracarboxylate Catalyzed Carbene Reactions
46 of 100
Leveraging Organic Synthesis to Disrupt and Understand Essential Bacterial Processes
47 of 100
Targeting Bacterial Tolerance and Resistance with Small Molecules
48 of 100
Design, Synthesis, and Utility of Group IX Metal Catalysts for C–H Functionalization
49 of 100
Synthesis and Biological Investigation of Natural Product-Inspired Antimicrobial Compounds
50 of 100
Synthetic Investigations into Small Molecules with Antibacterial Potential
51 of 100
Site-Selective and Enantioselective C-H Functionalization of Unactivated C–H Bonds in the Presence of Nitrogen Functionality
52 of 100
Computational Development of Macrocyclic Drug Hits and Synthetic Strategy towards Peptide Macrocyclization
53 of 100
Glyoxal-based Caging of Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Viral Infections
54 of 100
Exploring the Influence of Dirhodium Catalyst Structure on the Regio- and Stereoselectivity Properties of Donor/Acceptor Carbenes
55 of 100
Synthesis, Structure-Activity Relationship, and Biological Evaluation of Subunit-Selective NMDA Receptor Modulators
56 of 100
Synthesis of septanose glycals and progress towards endo-mode cyclization of polyepoxides
57 of 100
Synthesis of small molecule therapeutics and ligands utilizing rhodium carbenoid chemistry
58 of 100
Modification of Quorum Quenching Analogs from Schinus terebinthifolia Fruit Extract
59 of 100
Design and Synthesis of New Liver Receptor Homolog-1 Modulators and Probes
60 of 100
Allylic C-H Functionalization Studies on Allylbenzene Derivatives
61 of 100
A Tale of Two Chemistries: Dynamics of Delay-Coupled Belousov-Zhabotinsky Oscillators; TrkB Activators: A Review; Synthesis of TrkB Agonists
62 of 100
The Development of Complementary Allylic C-H Amination and Amidation Conditions for the Regioselective Functionalization of Group IX MCp*-π-Allyl Intermediates
63 of 100
Site-selective and Stereoselective Functionalization of Non-Activated C–H Bond
64 of 100
Modification of Tetrahydroisoquinoline-and-Mopholine-Containing CXCR4 Antagonists with Morpholine Analogs
65 of 100
Radical Spirocyclization via Organic Photoredox Catalysis
66 of 100
Kinetic Studies of Rhodium(III)-Catalyzed Allylic C-H Amination of Disubstituted Olefins
67 of 100
The Design, Synthesis, and Biological Evaluation of Novel Prodrugs and Antiviral Agents for HIV and Other Chronic Viral Infections
68 of 100
The Development and Mechanistic Studies of Group(IX)Cp*-Catalyzed Allylic C–H Functionalization Reactions Proceeding via a π-allyl Intermediate
69 of 100
Structural Requirements of the Sulfonyl Prolinate Ligands for Dirhodium Catalysis
70 of 100
Developing First-Row Transition Metal Complexes for Green Catalytic C–H Activation and Oxidations
71 of 100
Unusual Paradigms in Selective Synthesis: Part 1: Toward the Synthesis of Racemic and Enantioenriched HIOC; Part 2: Fluorinated Alcohols: Powerful Promoters for the Ring-Opening Reactions of Epoxides with Carbon Nucleophiles
72 of 100
GluN2C/D subunit selective antagonist for NMDARs: 997 Series
73 of 100
Synthetic Applications of Dirhodium(II) Catalysis
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EXPANDING THE SCOPE AND APPLICATION OF N-SULFONYL-1,2,3-TRIAZOLES AS ALTERNATE PRECURSORS TO DONOR/ACCEPTOR RHODIUM CARBENES
75 of 100
Promysalin and CD437: Compounds Investigating New Antibacterial Mechanisms
76 of 100
Optimization of Rh2(S-TPPTTL)4 Through Ligand Diversification
77 of 100
Development of Intermolecular Couplings of Aryl Radical Species with Olefins
78 of 100
Investigation of the Bridgehead Substituent of the Leading LRH-1 Agonists
79 of 100
The Synthesis and Application of a Series of C4-Symmetric Dirhodium Catalysts Derived from 1-(2-Chlorophenyl)-2,2-Diphenylcyclopropanecarboxylate Ligands
80 of 100
Radical Conjugate Addition of N-Heterocycles and Tertiary Amines
81 of 100
Structural Factors of Radical-Enhanced Intersystem Crossing of Organic Chromophores
82 of 100
Broadening the applications of rhodium donor/acceptor carbene mediated C–H functionalization
83 of 100
Synthesis of bulky 1,4,7-triazacylcononanes, including asymmetric derivatives; Esterification by aryl-diselenide catalyzed redox condensation; 1-amino-3,4-difluorocyclopentane-1-carboxylic acids as PET imaging agents
84 of 100
Natural and Synthetic Compounds as Tools to Overcome Antibiotic Resistance
85 of 100
Synthesis of a novel C-nucleoside prodrug for treatment of Hepatitis B
86 of 100
Development and Optimization of Monosubstituted and Disubstituted Alkene Synthesis for Future Intramolecular Alkene Hydroalkoxylation Reactions
87 of 100
Intercepting Photochemically Generated Aminoalkyl and Aryl Radical Intermediates to Access Complexity Quickly
88 of 100
In Situ Kinetic Studies on Rhodium (II) Carboxylate Catalysts with Cyclopropanation Reactions
89 of 100
Structure, Synthesis, and Reactivity: Intentional Design Approaches to Agonists for Liver Receptor Homolog-1 and Photochemical Arene Dearomatization
90 of 100
Structure-Activity Relationship and Quantitative Structure-Activity Relationship of GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor
91 of 100
The Design, Synthesis, and Biological Evaluation of Subunit-Selective Modulators of the N-Methyl-D-Aspartate Receptor
92 of 100
Complementary Approaches to Combat Antibacterial Resistance: Metal-binding Small Molecules and Quaternary Ammonium Compounds
93 of 100
Development and Applications of a New Dirhodium(II) Tetracarboxylate Catalyst and Asymmetric Cyclopropanation of Heterocyclic Compounds
94 of 100
The Iterative Design of Aptamer-Functionalized Membranes to Enable Detection, Sequestration, and Recovery of Small-Molecule Compounds
95 of 100
The Control of Stereoselectivity and Regioselectivity both in Intramolecular and Intermolecular Carbon-Oxygen Bond-Forming Reactions
96 of 100
Dearomative Photocatalytic Hydroalkylation and Lipophilic Prodrugs
97 of 100
Synthesis of a Click-Compatible Phenylacrylamide to Probe A-to-I RNA Editing
98 of 100
Arene Dearomatization via Radical Hydrofunctionalization
99 of 100
Computational and Experimental Studies of Allylic C-H Functionalization of Internal Olefins via Group IX Metal-Pi-Allyl Intermediates and Invention of a Chiral Indenylrhodium(III) Catalyst
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